Evaluation of maxillary alveolar ridge changes (bone quantity and quality as revealed by radiographic and Histomorphometry ) utilizing microfragmented adipose tissue loaded on allograft versus allograft only for maxillary posterior ridge preservation

All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on allograft will be utilized for the study group and allograft only for the control group.

After 3-6 months, assessment of dimensional changes ( RG height & width) on CBCT is performed and Histomorphometry will be evaluated via core biopsy at the time of implant placement in both groups.

Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height and width from base line (1week) to 3-6 months postoperatively.

Inclusion Criteria:

• Patients requiring implant treatment after tooth extraction due to either unrestorable caries lesions or affected periodontium.

Age group: above 18 years

• Remaining natural teeth have good periodontal tissue support and occlusion showed sufficient inter arch space for future prosthesis.

Exclusion Criteria:

• • General contraindications to implant surgery.

  • Subjected to irradiation in the head and neck area less than 1 year before implantation.
  • Poor oral hygiene and motivation.
  • Severe bruxism or clenching.
  • Systemic, immunologic or debilitating diseases that could affect normal bone healing & local pathosis.
  • Treated or under treatment of intravenous amino-bisphosphonates.
  • Active infection or severe inflammation in the area intended for implant placement.
  • Patients participating in other studies, if the present protocol could not be properly followed.
  • Heavy somkers

All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on allograft will be utilized for the study group and allograft only for the control group.

For both groups: All Patients of both groups will be evaluated radiographically immediately and after 3- 6 months post-operative by cone beam CT scan to record Alveolar ridge height and width.

After 6 months, patients will be evaluated histomorphometrically via core biopsy at the time of implant placement and radiographically via assessment of ridge height on CBCT.

Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height and width from base line (1week) to 6 months postoperatively.