Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Cardiac surgery is a bleeding-risk surgery and frequently requires blood transfusion. Intraoperative autotransfusion devices are used to aspirate, process and retransfuse patients' blood. These devices are effective in recovering red blood cells and limiting the need for transfusion of packed red blood cells. Some devices, such as I-SEP's SAME®, can also be used to recover platelets, but their effectiveness has not yet been evaluated in real-life situations. The aim of this study is therefore to investigate the evolution of platelet counts following the use of an intraoperative recovery device in adult patients undergoing standard cardiac surgery
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Autotransfusion device | Device | Standard cardiac surgery using I-SEP and SAMEâ„¢ autotransfusion device |
| Measure | Description | Time Frame |
|---|---|---|
| Platelet count | Study the evolution of platelet counts following the use of I-SEP's SAMEâ„¢ autotransfusion device in major patients undergoing standard cardiac surgery | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |
| Measure | Description | Time Frame |
|---|---|---|
| To study the evolution of platelet count following the use of the autotransfusion device (other than SAME) in major patients undergoing standard cardiac surgery. | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device | |
| To study the evolution of platelet function (flow cytometry and flow aggregation) following the use of a autotransfusion device in major patients undergoing standard cardiac surgery. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients addressed in a university hospital for cardiac surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Charles TACQUARD, PHU | Contact | +33 6 69 55 16 08 | charlesambroise.tacquard@chru-strasbourg.fr |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpitaux Universitaires de Strasbourg | Recruiting | Strasbourg | Bas-Rhin | 67091 | France |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Platelet-poor plasma Used autotransfusion device
| Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |
| Study the evolution of platelet function according to the autotransfusion device used. | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |
| Study post-operative bleeding volume as a function of autotransfusion device type. | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |
| Study the volume of labile blood product transfusion according to the autotransfusion device used. | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |
| Study the intensity of post-operative inflammatory syndrome as a function of the autotransfusion device used. | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |
| Study platelet adhesion to the autotransfusion device membranes using electron microscopy. | Before the use of blood sparing system and 5 minutes after the end of the infusion of blood from the autotransfusion device |