Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The effects of the hormones melatonin and cortisol, which play a highly effective role in regulating the sleep-wake cycle, on teeth grinding will be scientifically evaluated. Based on the research results, more effective methods for treating patients suffering from bruxism may be identified.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Evaluation of Melatonin and Cortisol Levels in Individuals with Bruxism |
| |
| 2 | Evaluation of Melatonin and Cortisol Levels in Individuals without Bruxism |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| The investigation of melatonin and cortisol levels in the saliva | Diagnostic Test | In the related study, patient data from individuals who visited the Oral and Maxillofacial Radiology clinic at Van Yüzüncü Yıl University Faculty of Dentistry with complaints of bruxism will be used. The diagnosis of bruxism will be made based on clinical data. Diagnoses will be made by Dr. Sema KAYA using clinical findings such as patient history used for the current diagnosis of bruxism, tooth wear, tooth mobility, pain in the temporomandibular joint (TMJ), headaches, pain in the chewing muscles, hypertrophy, and a feeling of fatigue. Before taking the saliva samples, patients will be asked to rinse their mouths with sterile water, and then they will be asked to spit into sterile plastic containers. After approximately 3 mL of saliva is collected, it will be transferred to appropriate Eppendorf tubes and stored at -80°C. Melatonin and cortisol levels will later be analyzed using the enzyme-linked immunosorbent assay (ELISA) method. |
| Measure | Description | Time Frame |
|---|---|---|
| levels of melatonin | individuals with bruxism | Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months. |
| levels of cortisol | individuals with bruxism | Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months. |
Not provided
Not provided
Inclusion Criteria:
- Individuals without any known hormonal diseases, not using antidepressants or medications that could alter saliva content, without degenerative diseases affecting the salivary glands, without cysts or tumors affecting the temporomandibular region, and not undergoing insomnia treatment will be included in the study
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
ndividuals with and without bruxism
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sema Kaya | Contact | +90 432 225 17 22 | +905540062682 | semakaya@yyu.edu.tr |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D002012 | Bruxism |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
| D006184 | Habits |
| D001519 | Behavior |
Not provided
Not provided
Not provided
Not provided
Not provided
The melatonin and cortisol levels in the saliva of patients will be examined. Since saliva will be collected, it contains DNA. However, it will not be used for research purposes.
|