A Phase 3 Randomized Double-blind Study of Adjuvant Pembrolizumab With or Without V940 in Participants With Resectable Stage II to IIIB (N2) NSCLC Not Achieving pCR After Receiving Neoadjuvant Pembrolizumab With Platinum-based Doublet Chemotherapy (INTerpath-009)
A Phase 3 Randomized Double-blind Study of Adjuvant Pembrolizumab With or Without V940 in Participants With Resectable Stage II to IIIB (N2) NSCLC Not Achieving pCR After Receiving Neoadjuvant Pembrolizumab With Platinum-based Doublet Chemotherapy (INTerpath-009)
The goal of this study is to learn if people who receive intismeran autogene and pembrolizumab after surgery are cancer-free longer than people who receive placebo and pembrolizumab. Researchers want to know if giving intismeran autogene and pembrolizumab after surgery can help prevent the cancer from coming back in people with non-small cell lung cancer (NSCLC) whose tumors did not respond completely to treatment before surgery (neoadjuvant treatment).
Inclusion Criteria:
The main inclusion criteria include but are not limited to the following:
Exclusion Criteria:
The main exclusion criteria include but are not limited to the following:
Trialsites@msd.com1-888-577-8839
Gilbert, Arizona 85234, United States
480-256-6444
Tucson, Arizona 85719, United States
Los Angeles, California 90033, United States
Los Angeles, California 90404, United States
San Francisco, California 94158, United States
Aurora, Colorado 80045, United States
Colorado Springs, Colorado 80909, United States
Greeley, Colorado 80631, United States
Westminster, Colorado 80023, United States
New Haven, Connecticut 06510, United States
Norwich, Connecticut 06360, United States
Fort Lauderdale, Florida 33316, United States
Miami, Florida 33176, United States
Chicago, Illinois 60637, United States
Osage Beach, Missouri 65065, United States
East Syracuse, New York 13057, United States
New York, New York 10011, United States
New York, New York 10029, United States
New York, New York 10065, United States
Charlotte, North Carolina 28204, United States
Winston-Salem, North Carolina 27103, United States
Corvallis, Oregon 97330, United States
Bethlehem, Pennsylvania 18015, United States
Chattanooga, Tennessee 37403, United States
Nashville, Tennessee 37203, United States
Tyler, Texas 75701, United States
Silverdale, Washington 98383, United States
Caba., Buenos Aires C1431FWO, Argentina
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Ciudad Autonoma de Buenos Aires., Buenos Aires C1199ABB, Argentina
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Buenos Aires, C1426ANZ, Argentina
Brussels, Bruxelles-Capitale, Region de 1200, Belgium
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Natal, Rio Grande do Norte 59062-000, Brazil
Passo Fundo, Rio Grande do Sul 99010-260, Brazil
Porto Alegre, Rio Grande do Sul 91359-200, Brazil
Santa Cruz do Sul, Rio Grande do Sul 96830-180, Brazil
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Tours, Centre-Val de Loire 3700, France
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Törökbálint, Pest County 2045, Hungary
Kaposvár, Somogy County 7400, Hungary
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Rome, Roma 00128, Italy
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Poznan, Greater Poland Voivodeship 60-569, Poland
Krakow, Lesser Poland Voivodeship 31-202, Poland
Wroclaw, Lower Silesian Voivodeship 53-439, Poland
Warsaw, Masovian Voivodeship 01-138, Poland
Przemyśl, Podkarpackie Voivodeship 37-700, Poland
Gdansk, Pomeranian Voivodeship 80-214, Poland
Olsztyn, Warmian-Masurian Voivodeship 10-357, Poland
Kielce, Świętokrzyskie Voivodeship 25-734, Poland
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Bristol, Bristol, City of BS2 8ED, United Kingdom
London, Kensington and Chelsea SW3 6JJ, United Kingdom
London, London, City of SW3 6JJ, United Kingdom
Metropolitan Borough of Wirral, CH63 4JY, United Kingdom
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