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Posterior fossa surgery represents on of the most demanding procedure in neurosurgery. Retrosygmoid (RS), key-hole retrosygmoid (KR) and cerebellar hemispheric (CH) are the most common approaches used to access in this area. Despite they are not technically difficult to perform, these approaches can be burdened by postoperative cerebrospinal fluid (CSF) leakage, both at short and long-term follow-up, with an high risk of meningitis. Many techniques were employed to avoid this risk, but it can still be estimated between 2% and 11% according to literature1-4. Spena et al. reported a CSF leakage rate of 6.8% in a previous experience5. As a consequence, newer efforts are necessaries to avoid this potentially lethal complication. By this explorative study, we want to retrospectively analyzed our experience with a newer technique of bone closure, called O'Ring, in patients subdued to posterior fossa surgery by RS, KR and CH approaches, focusing on postoperative CSF leakage (primary objective), wound complications and subcutaneous CSF collections (secondary objectives).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients operated for a disease located in posterior fossa | Patients operated for a disease located in posterior fossa for which a RS, KR or CH approach has to be performed. Patients between January 2018 and October 2023 will be considered for the study. Lacking of clinical, radiological and surgical data represe |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| O-ring technique | Procedure | "O-ring technique." consists on a different arrangement of fibrin-glue on a polymethilmetacrylate cranioplasty, with the aim to create a gasket to prevent CSF leakage |
| Measure | Description | Time Frame |
|---|---|---|
| to estimate incidence of postoperative CSF leakage | cumulative incidence of postoperative CSF leakage | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| to estimate incidence CSF leakage at 1- and 3-months of follow-up. | cumulative incidence of CSF leakage at 1- and 3-months follow-up | 1 and 3 months |
| to estimate the incidence of wound complications postoperatively and at 1- and 3-months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients operated for a disease located in posterior fossa for which a RS, KR or CH approach has to be performed. Patients between January 2018 and October 2023 will be considered for the study.Lacking of clinical, radiological and surgical data represented exclusion criteria.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SC Neurochirurgia, Fondazione IRCCS Policlinico San Matteo | Pavia | Pavia | 27100 | Italy |
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cumulative incidence of wound complications postoperatively and at 1- and 3-months follow-up
| 1 and 3 months |
| to estimate the incidence of subcutaneous CSF collections postoperatively and at 1 and 3-months radiological follow-up | cumulative incidence of subcutaneous CSF collections postoperatively and at 1 and 3-months radiological follow-up | 1 and 3 months |