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We ought to investigate if hip fracture patients suffering from frailty have higher inflammatory burden according to simple inflammatory biomarkers.
Frailty (F) is a prevalent syndrome among elderly patient with hip fractures (HF) and has been linked to poor prognosis. Inflammatory biomarkers have been used as prognostic indexes in patients with HF. We ought to investigate if hip fracture patients suffering from frailty have higher inflammatory burden according to simple inflammatory biomarkers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| hip fracture patients treated with surgery | Hip fracture patients treated with surgery. Frailty will be categorized based on the validated Groningen Frailty Indicator (GFI) |
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| Measure | Description | Time Frame |
|---|---|---|
| Frailty status | Frailty will be categorized based on the validated Groningen Frailty Indicator (GFI) as non-frail (NF, score 0,1), pre-frail (PF, score 2, 3) and severe frail (SF, score >4). | preoperatively |
| Inflammatory biomarkers | Upon admission and immediate before surgery upper limits of white blood cells (WBC) within normal range (WBC >8 10^3/μL), NLR (neutrophils/lymphocytes), PLR (platelets/lymphocytes), CRP (C-reactive protein) and CLR (CRP/lymphocytes), will be recorded. | preoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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hip fracture patients treated with surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eleni Arnaoutoglou, Professor | Contact | +302413502952 | earnaout@gmail.com | |
| Maria Ntalouka, MD, PhD, MSc | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Eleni Arnaoutoglou, Professor | University of Thessaly | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Larissa University Hospital | Recruiting | Larissa | Thessaly | 41110 | Greece |
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| ID | Term |
|---|---|
| D000073496 | Frailty |
| D006620 | Hip Fractures |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
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| UHL | Recruiting | Larissa | Thessaly | 41110 | Greece |
|
| D014947 | Wounds and Injuries |
| D025981 | Hip Injuries |
| D007869 | Leg Injuries |