Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.
pulpotomy by using 3 materials. The first group(control group ) uses hydroxyapatite material as a pulpotomy agent, and the second group uses L-PRF as a pulpotomy agent. the third group uses combined material (L-PRF = Nano hydroxyapatite )as a pulpotomy agent .. then assesses the clinical and radiographic result of the 2 interventions group with control group
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| hydroxyapatite | Experimental | using hydroxyapatite as a pulpotomy agent and reviewing its clinical and radiographic performance compared to the other groups |
|
| L-PRF | Experimental | using L-PRF as a pulpotomy agent and assessing the clinical and radiographic result compared to other groups |
|
| L-PRF combined with Nano-hydroxyapatite | Experimental | using the combined material (nanohydroxyapatite mixed to L-PRF ) and assessing the clinical and radiographic result compared to other groups |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pulpotomy | Procedure | removal of the coronal pulp tissue and preservation of the radicular portion to ensure continuation of growth and vitality of tooth structure |
|
| Measure | Description | Time Frame |
|---|---|---|
| post operative Pain assessment | Pain evaluations were conducted preoperatively with numerical rating scale ( a verbal or writing determination of a pain level on a scale from 0 to 10, in which 0 represents no pain and 10 represents excruciating pain . | 6, 12, 24, 72hours and 7 days after treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Dentine bridge formation | evaluating the thickness of dentine bridge formed after the procedure by comparing immediate post operative CBCT with the one year follow up scans | 12 months post operative |
Not provided
Inclusion criteria:
Patients should be free from any systemic disease. Patients of either gender aged from 15-30. Patients will agree to the consent and will commit to a follow-up period. Soft tissues around the tooth are normal with no swelling or sinus tract. The tooth is restorable tooth has signs and symptoms of irreversible pulpitis of the mature root The tooth doesn't contain any internal or external resorption or periapical lesions.
The tooth should give a positive response to the cold test.
Exclusion criteria:
Pregnant and lactating females. Patients with Mental disturbance. Patients who could/would not participate in a 6-month follow-up. A tooth with immature roots. Patients with necrotic pulp.• tooth with periapical lesions or infections. Soft tissue having fistula or swelling Homoeostasis after 10 minutes can not be controlled after total pulpotomy
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| nada A metwally, master | Contact | 01122289353 | +02 | nadaaymaan55@gmail.com |
| toka A metwally, bachelor's | Contact | 01068681660 | +02 |
| Name | Affiliation | Role |
|---|---|---|
| wael K hussein, professor | future | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| future university in Egypt | Recruiting | Cairo | New Cairo | 11835 | Egypt |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D011672 | Pulpotomy |
| ID | Term |
|---|---|
| D004708 | Endodontics |
| D003813 | Dentistry |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|