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The goal of this experimental study is to evaluate the efficacy of five educational strategies for recognizing early symptoms of cerebrovascular disease (CVD) in the general adult population. The main questions it aims to answer are:
- How effective are the strategies RAPIDO, CORRE, DALE, CAMALEON, and ICTUS 911 in improving the recognition of early CVD symptoms?
Researchers will compare these strategies to determine which one leads to the highest increase in symptom recognition. Participants will receive a brief educational session on one of the five strategies and will:
The primary outcome is the improvement in SAQ scores, and the secondary outcome is the proportion of participants achieving adequate knowledge of CVD symptoms.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| RAPIDO Strategy Arm | Experimental | Participants in this arm receive educational training based on the RAPIDO strategy, an acronym developed to raise awareness of stroke symptoms among the Spanish-speaking community. This strategy is modeled after the English FAST mnemonic and focuses on the rapid identification of stroke symptoms. |
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| CORRE Strategy Arm | Experimental | Participants in this arm are trained using the CORRE strategy, created by a Colombian neurologist. It mirrors the structure of other mnemonic-based interventions and emphasizes the importance of quickly recognizing and acting upon early stroke symptoms. |
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| DALE Strategy Arm | Experimental | Participants in this arm are educated using the DALE strategy, developed in 2012 by researchers at the University of Guadalajara. Similar to the RAPIDO strategy, DALE adapts the FAST mnemonic for the Spanish-speaking population, promoting quick recognition and response to cerebrovascular symptoms. |
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| CAMALEON Strategy Arm | Experimental | In this arm, participants receive training based on the CAMALEON strategy, a mnemonic created in Costa Rica with the support of the pharmaceutical industry. The approach is designed to facilitate the recognition of early stroke symptoms by adapting the FAST mnemonic to Spanish. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mnemonic-Based Educational Training for Stroke Symptom Recognition | Behavioral | This is a Culturally Adapted Mnemonic-Based Educational Strategies for Rapid Stroke Symptom Recognition in the Spanish-Speaking Population. It uses five distinct mnemonic strategies (RAPIDO, CORRE, DALE, CAMALEON, ICTUS 911), each specifically tailored for a Spanish-speaking audience. Aims to improve the recognition of early cerebrovascular disease symptoms, differentiating it from other clinical studies that might focus on different health conditions or target populations. Emphasizes its focus on rapid action by educating participants about stroke symptoms and the importance of contacting emergency services (911). |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Stroke Awareness Questionnaire (SAQ) Score | This measure will assess the change in participants' knowledge of stroke symptoms before and after receiving the educational intervention. The SAQ evaluates awareness of stroke symptoms, risk factors, and appropriate responses to suspected stroke events. | Pre-intervention and 7 days post-intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of Participants with Adequate Knowledge of Stroke Symptoms | This outcome measures the proportion of participants who achieve a predetermined "adequate knowledge" score on the SAQ, defined as correctly identifying at least 3 stroke symptoms and understanding the need to contact emergency services (911) within 3 hours of symptom onset. | 7 days post-intervention. |
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Inclusion Criteria:
Exclusion Criteria:
Elimination Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital General de Zona #2 | Aguascalientes | Aguascalientes | 20190 | Mexico |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40884082 | Derived | Marquez-Romero JM, Sanchez-Ramirez KI, Perez-Malagon CD, Padilla-Lopez J, Ford GA, Zhao J, Liu R. Efficacy of five strategies to improve stroke action awareness in Spanish-speaking adults: A randomized comparison. Int J Stroke. 2026 Mar;21(3):419-429. doi: 10.1177/17474930251378229. Epub 2025 Aug 30. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ICTUS 911 Strategy Arm | Experimental | Participants in this arm are educated using the ICTUS 911 strategy, which differs from the other four in that it is not directly based on a literal translation of FAST. Instead, it focuses on recognizing stroke symptoms and immediately calling emergency services (911) upon suspicion of a stroke. |
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| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |