Sensitivity and Specificity of Leucocytes Profiling Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial

Sensitivity and Specificity of Leucocytes Subpopulation Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Clinical Trial

Leucocyte subpopulation and platelet indices analysis can predict clinical outcome

Inclusion Criteria:

• Adult population of both sex, aged 20 or older admitted to the ICU with a diagnosis of sepsis were screened for inclusion within 48 h of presentation to the hospital. Sepsis was defined as per the Sepsis-3 definition, 6 ie, the presence of suspected or documented infection with organ dysfunction determined by an acute increase of sequential organ failure assessment (SOFA) score by 2 or more points

Exclusion Criteria:

• Patient refusal.
• History of surgery in the last 7 days from admission.
• Immunocompromised population ( post-transplantation, steroid use > 5 mg per day, malignancy, HIV, on chemotherapy).
• History of platelet transfusion one week before admission.
• Bone marrow transplanted population on steroid therapy.
• Von-Willebrand disease.
• Myelodysplastic or proliferative patients.
• Blood dyscarsiasis
• Obestetric parturients.