Electro-Acupuncture for Obese Patients With Insulin Resistance

Electro-acupuncture for the Obese Patient With Insulin Resistance: a Randomized Sham-controlled Clinical Trial

This clinical trial aims to evaluate the efficacy and safety of electro-acupuncture for obese patients with insulin resistance. 60 participants will be randomized and allocated to either the electro-acupuncture arm or the sham acupuncture arm.

Inclusion Criteria:

• Men and women aged between 21 and 65 years old
• BMI ≥ 25 kg/m2
• HOMA-IR ≥ 2.14, (HOMA-IR = fasting insulin (ųU/mL)* fasting glucose (mmol/L)/22.5)
• Not receiving any other weight control measures or any medical and/or drug history in the last 3 months

Exclusion Criteria:

• Diabetes mellitus
• Treating with drugs that may affect insulin sensitivity
• Changes 10% of usual body weight in the previous 6 months weight
• Endocrine diseases, including thyroid disorder, pituitary disorder, sex gland disorder, etc.
• Heart diseases, including arrhythmia, heart failure, and myocardial infarction, participants with pacemakers
• Allergy and immunology diseases
• Bleeding tendency
• Pregnant or lactating women
• Impaired hepatic or renal function
• Stroke or unable to exercise