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The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).
Construct a predictive model for biochemical recurrence (BCR) in patients after radical prostatectomy using imaging parameters from preoperative 18F-PSMA-1007 PET/MRI, and compare the predictive performance of this model with existing clinical models. Data from three centers will be collected, with datasets from two centers used as the training set for the selection of predictive factors and model construction, while the dataset from the remaining center will serve as the validation set to assess the predictive performance of the model for BCR after prostatectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Shanghai East Hospital, Tongji University School of Medicine | Patients diagnosed with prostate cancer undergoing PSMA PET/MR examination prior to surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observe | Other | Ruijin |
|
| Measure | Description | Time Frame |
|---|---|---|
| 18F-PSMA-1007 PET/MR image parameters | Before surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Biochemical recurrence-free survival time | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
1.Surgery or endocrine therapy is performed prior to the examination
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Male
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Patients diagnosed with prostate cancer undergoing PSMA PET/MR examination prior to surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ruijin Hospital affiliated to Shanghai Jiao Tong University of Medicine | Shanghai | China |
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| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| D005832 |
| Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |