1. To observe the failure rate of S-ICD screening in HCM patients at high risk of SCD.
2. To observe the incidence of IAS in HCM patients with S-ICD implantation and explore the related factors of IAS.

The study was a multicenter, prospective, observational study that prospectively included HCM patients assessed as meeting the ICD implantation indication at Fuwai Hospital and National Collaborative Hospitals from July 1, 2024 to June 30, 2027, for pre-operation screening of S-ICD, and follow-up of patients eventually implanted with S-ICD.

Inclusion Criteria:

• HCM patients assessed as meeting the ICD implantation indication

Exclusion Criteria:

• Combined with bradycardia with pacing indications;
• Frequent monomorphic ventricular tachycardia require ATP therapy;
• With indications of CRT;
• Combined with other diseases, life expectancy is less than 1 year.

The study was a multicenter, prospective, observational study that prospectively included HCM patients assessed as meeting the ICD implantation indication at Fuwai Hospital and National Collaborative Hospitals from July 1, 2024 to June 30, 2027.