ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France. To select patients with the best prognosis, the inclusion criteria defined were strict. This led to an over-selection of patients and a significant reduction in the number of eligible patients. A balance needed to be struck between over-selecting patients and maintaining the expertise of medical and paramedical teams in the field. In addition, it has also been shown that ECPR also increases the number of organs and transplants.

In February 2024, the criteria for inclusion in the protocol were redefined to include any witnessed non-traumatic cardiac arrest, whatever the initial rhythm. This simplification should enable more patients to be included in the procedure.

The aim of the study is to assess the patient's outcome

Inclusion Criteria:

• Out-of-hospital cardiac arrest
• enrolled in the ECPR program
• 18 years old or more
• Low-flow estimated <60minutes

Exclusion Criteria:

• traumatic cardiac arrest
• major comorbidities

All patients presenting with refractory out-of-hospital cardiac arrest and enrolled in the ECPR program in Nancy, France.

Inclusion criteria for the ECPR program are the following:

• Age: 18-65 years
• No major comorbidity
• Witnessed non traumatic cardiac arrest
• Low-flow to ECPR estimated of less than 60 minutes