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| ID | Type | Description | Link |
|---|---|---|---|
| 1R01AI182165 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Children's Hospital of Philadelphia | OTHER |
| American Academy of Pediatrics | OTHER |
| University of Pennsylvania | OTHER |
| National Institute of Allergy and Infectious Diseases (NIAID) |
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This multi-site study assesses the impact of text message reminders on the receipt of COVID-19 and influenza text message reminders takes place primarily in practices from the American Academy of Pediatrics (AAP) Pediatric Research in Office Settings (PROS) network.
The study is to be conducted over the 1st season (September 2024-April 2025) as an effectiveness trial and the 2nd (September 2025-April 2026) as a replication study. This protocol covers the first season. Parents of eligible children who are 6 month-17 year-old who are due for both a COVID-19 and influenza vaccine will be sent text messages. Within each practice site, parents of eligible children will be randomized to receive either: 1) combined COVID-19 and influenza vaccine text message reminders, 2) COVID-19 reminders alone, 3) influenza reminders alone, or 4) no reminders (usual care).
Randomization is to be stratified by practice site, age group and prior year's COVID-19/influenza vaccine history. Messages will be sent centrally and managed by the research team.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Text message influenza and COVID-19 vaccine reminders | Experimental | Text message reminders for both influenza and COVID-19 vaccinations |
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| Text message influenza vaccine reminders | Experimental | Text message reminders only for influenza vaccination |
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| Text message COVID-19 vaccine reminders | Experimental | Text message reminders only for COVID-19 vaccination |
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| Usual Care | No Intervention | Usual care has no text message |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Text message influenza vaccine reminders | Behavioral | Text message influenza vaccine reminders |
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| Measure | Description | Time Frame |
|---|---|---|
| Timeliness of influenza vaccination | Days from study start to influenza vaccine up to December 31 each year | Up to December 31 each year, up to ~90 days |
| Timeliness of COVID-19 vaccination | Days from study start to COVID-19 vaccine up to December 31 each year | Up to December 31 each year, up to ~90 days |
| Measure | Description | Time Frame |
|---|---|---|
| Timeliness of influenza vaccination | Days from study start to influenza vaccine up to April 30 each year | Up to April 30 each year, up to ~210 days |
| Timeliness of COVID-19 vaccination | Days from study start to COVID-19 vaccine up to April 30 each year |
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Inclusion Criteria:
Child that:
Receives care at study site
Language listed in electronic health record is English or Spanish
Has not opted out of text messages from practice
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Melissa Stockwell, MD MPH | Columbia University | Principal Investigator |
| Alex Fiks, MD MSCE | Children's Hospital of Philadelphia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| American Academy of Pediatrics | Itasca | Illinois | 60143 | United States | ||
| Columbia University Irving Medical Center |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Dec 31, 2025 | |
| Reset | Jan 20, 2026 |
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| NIH |
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| Text message COVID-19 vaccine reminders | Behavioral | Text message COVID-19 vaccine reminders |
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| Text message influenza and COVID-19 vaccine reminders | Behavioral | Text message influenza and COVID-19 vaccine reminders |
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| Up to April 30 each year, up to ~210 days |
| Percentage of Participants Who Received Influenza Vaccine by December 31 Each Year | Receipt of influenza vaccine by December 31 each year | ~3 months |
| Percentage of Participants Who Received COVID-19 Vaccine by December 31 Each Year | Receipt of COVID-19 vaccine by December 31 each year | ~3 months |
| Percentage of Participants Who Received Influenza Vaccine by April 30 Each Year | Receipt of influenza vaccine by April 30 each year | ~7 months |
| Percentage of Participants Who Received COVID-19 Vaccine by April 30 Each Year | Receipt of COVID-19 vaccine by April 30 each year | ~7 months |
| New York |
| New York |
| 10032 |
| United States |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | United States |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Dec 31, 2025 | Jan 20, 2026 |
| ID | Term |
|---|---|
| D007251 | Influenza, Human |
| D000086382 | COVID-19 |
| D000088823 | Vaccination Hesitancy |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D009976 | Orthomyxoviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012140 | Respiratory Tract Diseases |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D008171 | Lung Diseases |
| D000072758 | Vaccination Refusal |
| D016312 | Treatment Refusal |
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
| D001519 | Behavior |
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