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This pilot study is a first step in looking at the relationship between exercise and appetite in women with loss of control eating.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Rest, Fed Exercise, Fasted Exercise | Experimental | At Study Visit 2, participants will eat breakfast and rest (abstain from exercise). At Study Visit 3, participants will eat breakfast and exercise. At Study Visit 4, participants will abstain from breakfast and will engage in exercise. |
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| Rest, Fasted Exercise, Fed Exercise | Experimental | At Study Visit 2, participants will eat breakfast and rest (abstain from exercise). At Study Visit 3, participants will abstain from breakfast and will engage in exercise. At Study Visit 4, participants will eat breakfast and exercise. |
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| Fed Exercise, Rest, Fasted Exercise | Experimental | At Study Visit 2, participants will eat breakfast and exercise. At Study Visit 3, participants will eat breakfast and rest (abstain from exercise). At Study Visit 4, participants will abstain from breakfast and will engage in exercise. |
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| Fed Exercise, Fasted Exercise, Rest | Experimental | At Study Visit 2, participants will eat breakfast and exercise. At Study Visit 3, participants will abstain from breakfast and will engage in exercise. At Study Visit 4, participants will eat breakfast and rest (abstain from exercise). |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rest | Behavioral | Participants will eat breakfast but abstain from exercise |
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| Measure | Description | Time Frame |
|---|---|---|
| Relative Energy Intake | Relative energy intake for 24 hours will be calculated as absolute energy intake from the breakfast (if consumed), lunch, food reward value task, and take home cooler minus energy expenditure during exercise (or comparable time period during rest). | Food intake from 8 am to 8 am; Energy expenditure from approximately 9 am to 9:05 am and 9:25 to 9:30 am, coinciding with study condition (rest or exercise) |
| Measure | Description | Time Frame |
|---|---|---|
| Lactate | Lactate values | 30 minutes, pre-post exercise (or rest) |
| Acylated ghrelin | Acylated ghrelin | Immediately prior to lunch |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ohio University | Athens | Ohio | 45701 | United States |
Data may be shared on a public repository, such as the Open Science Framework
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| ID | Term |
|---|---|
| D001068 | Feeding and Eating Disorders |
| D056912 | Binge-Eating Disorder |
| D052018 | Bulimia Nervosa |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| C092779 | RE1-silencing transcription factor |
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| Fasted Exercise, Fed Exercise, Rest | Experimental | At Study Visit 2, participants will abstain from breakfast and will engage in exercise. At Study Visit 3, participants will eat breakfast and exercise. At Study Visit 4, participants will eat breakfast and rest (abstain from exercise) |
|
| Fasted Exercise, Rest, Fed Exercise | Experimental | At Study Visit 2, participants will abstain from breakfast and will engage in exercise. At Study Visit 3, participants will eat breakfast and rest (abstain from exercise). At Study Visit 4, participants will eat breakfast and exercise. |
|
| Fed Exercise | Behavioral | Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max. |
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| Fasted Exercise | Behavioral | Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast. |
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| Self-reported binge eating | Participants will rate the extent the following questions, considering the time frame "since yesterday morning at 8 am" on a 1 to 5 scale from "not at all" to "extremely": "While you were eating, to what extent did you feel a sense of loss of control?," "While you were eating, to what extent did you feel that you could not resist eating," "While you were eating, to what extent did you feel that you could not stop eating once you had started," and "While you were eating, to what extent did you feel driven or compelled to eat?" An answer of 4 or higher on any item will be categorized as binge eating present. Any reported binge eating on either day will be coded as binge eating being present | 24 and 48 hours after exercise/rest study visit |
| Food reward value | Number of trials according to task developed by Bodell and Keel 2015 | Approximately 3:30 pm day of study visit |
| D001519 | Behavior |