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This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.
Introduction:
This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.
Purpose: This study aims to assess the prevalence and factors associated with elevated platelet counts in people with sickle cell disease in the eastern region of Saudi Arabia.
Methods: This cross-sectional study at Majmaah University will analyze prerecorded data frfom the eastern region of Saudi Arabia to investigate the relationship between platelet counts and sickle cell disease, identifying associated factors and assessing the link .
Importance: To assess the relationship between platelet counts and disease severity in Pationt with SCD.
Aim :To investigate the relationship between platelet counts and SCD in the eastern region of the Kingdom of Saudi Arabia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Males | The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. |
| |
| Children | The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. |
| |
| Females | The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Platelets count | Diagnostic Test | the study include will take medical investigation data for all sickle cell patients. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Collecting platelet data for sickle cell anemia patients | Collecting platelet data for sickle cell anemia patients in males and female and children based on different ages, then analyzing them and studying their relationship | From January 2023 to December 2023 |
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Inclusion criteria: All the diagnosed patients of sickle cell disease regardless of age and gender.
Exclusion criteria: Patients without having sickle cell disease regardless of age and gender.
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The study will include a cohort of people with SCD who are registered at the Hereditary Blood center al-ahssa.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Khalid A Majrashi | Contact | 0533489978 | khalid77555@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Khalid A Majrashi | Majmaah University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Khalid Ali Majrashi | Dammam | Saudi Arabia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9531343 | Result | Wun T, Paglieroni T, Rangaswami A, Franklin PH, Welborn J, Cheung A, Tablin F. Platelet activation in patients with sickle cell disease. Br J Haematol. 1998 Mar;100(4):741-9. doi: 10.1046/j.1365-2141.1998.00627.x. | |
| 30186009 | Result | Shome DK, Jaradat A, Mahozi AI, Sinan AS, Ebrahim A, Alrahim M, Ebraheem MS, Mansoor EJ, Majed KS, Azeez Pasha SA. The Platelet Count and its Implications in Sickle Cell Disease Patients Admitted for Intensive Care. Indian J Crit Care Med. 2018 Aug;22(8):585-590. doi: 10.4103/ijccm.IJCCM_49_18. |
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| ID | Term |
|---|---|
| D000755 | Anemia, Sickle Cell |
| ID | Term |
|---|---|
| D000745 | Anemia, Hemolytic, Congenital |
| D000743 | Anemia, Hemolytic |
| D000740 | Anemia |
| D006402 | Hematologic Diseases |
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| ID | Term |
|---|---|
| D010976 | Platelet Count |
| ID | Term |
|---|---|
| D001772 | Blood Cell Count |
| D002452 | Cell Count |
| D003584 | Cytological Techniques |
| D019411 | Clinical Laboratory Techniques |
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| 33489197 | Result | Yee MEM, Batsuli G, Chonat S, Park S. Thrombocytosis with acquired von Willebrand disease in an adolescent with sickle cell disease. Clin Case Rep. 2020 Nov 20;9(1):457-460. doi: 10.1002/ccr3.3556. eCollection 2021 Jan. |
| D006425 |
| Hemic and Lymphatic Diseases |
| D006453 | Hemoglobinopathies |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D019937 |
| Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D006403 | Hematologic Tests |
| D010979 | Platelet Function Tests |
| D008919 | Investigative Techniques |
| D002468 | Cell Physiological Phenomena |
| D001790 | Blood Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |