NBI-NearFocus can assist cold snare polypectomy (CSP) to remove small colorectal polyps, but its specific efficacy is not clear.The aim of this study was to assess the efficacy of CSP with NBI-NearFocus evaluation of polypectomy sites for removal of small colorectal polyps. And then formulate a standard operating procedure for cold snare removal of polyps.

Inclusion Criteria:

① Outpatient or inpatient patients aged 18-85 years old;

② Untamed, subpodial, and flat polyps with a diameter of 5-9mm (Paris classification: O-Is O-Isp、O-IIa；JNET Classification: Typel, Type2A);

③ Patients who agree to participate in this study.

Exclusion Criteria:

• Individuals currently taking antiplatelet or anticoagulant drugs, or those with coagulation dysfunction (PT prolongation greater than 3 seconds);

  • Polyp diameter<5mm or ≥ 10mm, morphology does not conform or JNET classification ≥ Type 2B;

    • Individuals with severe heart, lung, liver and kidney dysfunction or severe mental disorders who cannot cooperate with the examination; ④ Patients with intestinal obstruction, inflammatory bowel disease, Lynch syndrome, and familial adenomatous polyposis diagnosis;

      • Pregnancy; ⑥ Those who fail to meet the requirements for bowel cleansing preparation (BBPS<6 points).