Xenograft with or Without Erythropoietin in Immediate Dental Implant

Evaluation of Bone Dimensional Changes After Using Xenograft with or Without Erythropoietin Around Immediate Implants in the Esthetic Zone: a Randomized Clinical Trial

The aim of this study is to evaluate changes in buccal bone thickness after immediate implant placement with xenograft mixed with erythropoietin in the anterior maxilla with a thin buccal bone

PICO:

Population: Patients with non-restorable tooth in anterior maxilla with thin buccal bone (less than 1mm) Intervention: Immediate implant placement with Xenograft mixed with Erythropoietin.

Control: Immediate implant placement with Xenograft alone.

• Inclusion criteria

  • Adult (≥18 years) with non-restorable maxillary teeth in the esthetic zone (upper right second premolar to upper left second premolar).
  • Intact with thin labial plate of bone (≤1mm).
  • The recipient site of the implant should be free from any pathological conditions.
  • Patients who are cooperative, motivated and hygiene conscious.
  • Appropriate crown height space to maintain favorable crown : implant ratio

• Exclusion criteria

  • Systemic conditions/diseases that contraindicate surgery.
  • Patients who have any habits that might jeopardize the osseointegration process, such as current smokers.
  • Patients with parafunctional habits that produce overload on implant, such as bruxism and clenching.
  • Patients with periodontal disease.
  • Alcohol or drug abuse.
  • Pregnant and lactating women.