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This study aims to investigate the impact of short term, two distinct dietary interventions, namely the Keto diet and Intermittent Fasting on oral health by measuring the severity of:
Objectives of the study
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| participants committed to keto diet | Active Comparator | The experimental intervention consisted of a KD without caloric restriction over a period of 4 weeks. Prior to the study period, the participants were instructed by a dietitian. The participants were provided with online brochure describing the main aspects of a KD and given a list of suitable foods with a very low carbohydrate content. They were advised to eat ad libitum but to limit their carbohydrate intake to a maximum of 20-40 g/day to derive at leasut 75%, 15-20%, and 5-10% of total energy from fats, protein, and carbohydrates, respectively. The participants were allowed to vary the food according to their preferences within the framework of the KD. |
|
| participants committed to intermittent fasting with calorie restriction | Active Comparator | The 16/8 TRF group was asked to consume their daily calorie intake during an 8-hour window during the daytime and then fast for the remaining 16 hours each day throughout the intervention period. During the 16 hours fasting, they were able to drink water, coffee and tea without sugar. Participants are encouraged to drink 6-8 glasses of water per day. They were free to arrange the 8-hour eating window based on personal preferences. This flexibility was expected to help the participants adapt to their individual lifestyles and to facilitate compliance with the dietary intervention. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| keto diet | Behavioral | They were advised to eat ad libitum but to limit their carbohydrate intake to a maximum of 20-40 g/day to derive at leasut 75%, 15-20%, and 5-10% of total energy from fats, protein, and carbohydrates, respectively. |
| Measure | Description | Time Frame |
|---|---|---|
| effect of keto diet on oral health | effect of keto diet on oral health by measuring the plaque index and bleeding on probing index | 30 days |
| effect of intermittent fasting on oral health | effect of intermittent fasting on oral health by measuring the plaque index and bleeding on probing index | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| The effect of keto diet on salivary inflammatory biomarkers | effect of keto diet on salivary inflammatory biomarkers ( IL-6, IL-1B, C-RP, TNF-A, LL-37) | 30 days |
| The effect of intermittent fasting on salivary inflammatory biomarkers |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Mustansiriyah | Baghdad | Street 6 | 10011 | Iraq |
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| intermittent fasting with calorie restriction | Behavioral | The 16/8 TRF group was asked to consume their daily calorie intake during an 8-hour window during the daytime and then fast for the remaining 16 hours each day throughout the intervention period. |
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effect of intermittent fasting on salivary inflammatory biomarkers ( IL-6, IL-1B, C-RP, TNF-A, LL-37)
| 30 days |
| comparing the effect of KD and IF on inflammatory biomarkers | comparing the effect of keto diet and intermittent fasting on salivary inflammatory biomarkers ( IL-6, IL-1B, C-RP, TNF-A, LL-37) | 30 days |
| comparing the effect of KD and IF on oral health | comparing the effect of KD and IF on oral health by measuring the plaque index and bleeding on probing index | 30 days |
| The effect of intermittent fasting on bodyweight | The effect of intermittent fasting on bodyweight loss for overweight and obese cl I participants | 30 days |
| The effect of keto diet on bodyweight loss | The effect of keto diet on bodyweight loss for overweight and obese cl I participants | 30 days |
| The effect of keto diet on salivary PH | The effect of keto diet on salivary PH ( an increase or decrease) | 30 days |
| The effect of intermittent fasting on salivary PH | The effect of intermittent fasting on salivary PH ( an increase or decrease) | 30 days |
| ID | Term |
|---|---|
| D005891 | Gingivitis |
| ID | Term |
|---|---|
| D007239 | Infections |
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D055423 | Diet, Ketogenic |
| ID | Term |
|---|---|
| D050528 | Diet, Carbohydrate-Restricted |
| D004035 | Diet Therapy |
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
| D004032 | Diet |
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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