The goal of this observational study is to explore the clinical influences associated with the development of intestinal barrier dysfunction in patients undergoing gastrointestinal surgery. The main question it aims to answer is:What clinical factors increase the probability of developing intestinal barrier dysfunction in patients after gastrointestinal surgery?

Inclusion Criteria:

• men or women aged 18-80 years
• expected feasible abdominal surgical treatment (partial gastrectomy, colorectal resection)
• no preoperative intestinal barrier dysfunction
• patients voluntarily participated in this study and signed an informed consent form.

Exclusion Criteria:

• Patients or their families refused to participate in this study
• chronic inflammatory diseases (e.g. inflammatory bowel disease, chronic hepatitis, chronic pancreatitis, chronic peptic ulcer, etc.)
• history of antibiotic administration in the last 2 weeks
• severe cognitive impairment and other inability to cooperate preoperative neoadjuvant radiotherapy
• combined with severe hepatic, renal, and cardiac insufficiency patients.

People undergoing gastrointestinal surgery

Research not yet completed