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This research employs a cross-sectional study and a retrospective cohort study to analyze the liver safety of statin use among inpatients in the neurology department in China from different perspectives. The aim is to supplement evidence-based medicine and provide guidance for the clinical use of statins.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cross-sectional study and retrospective cohort study | This research was conducted in two phases. Initially, a cross-sectional study was performed to assess the correlation between statin usage prior to hospital admission and the initial state of liver enzymes among patients. Subsequently, a retrospective cohort study was undertaken, wherein patients who had not been on statins prior to admission were categorized into two groups based on their statin usage post-admission. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| stain | Other | This research was conducted in two phases. Initially, a cross-sectional study was performed to assess the correlation between statin usage prior to hospital admission and the initial state of liver enzymes among patients. Subsequently, a retrospective cohort study was undertaken, wherein patients who had not been on statins prior to admission were categorized into two groups based on their statin usage post-admission. |
| Measure | Description | Time Frame |
|---|---|---|
| Aspartate aminotransferase(AST) | The specific value of AST, whether the AST was more than 1 times the upper limit of normal (>1×ULN), and whether it was more than 3×ULN. | 4weeks after admission. |
| Alanine aminotransferase(ALT) | The specific value of ALT, whether the ALT was more than 1 times the upper limit of normal (>1×ULN), and whether it was more than 3×ULN. | 4 weeks taken after admission. |
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Inclusion Criteria:
Exclusion Criteria:
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The study included patients admitted to the Department of Neurology at Yueyang Hospital for cerebrovascular diseases, headaches, dizziness, and vertigo from June 2020 to February 2023.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai Yueyang Integrated Medicine Hospital | Recruiting | Shanghai | Shanghai Municipality | China |
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| ID | Term |
|---|---|
| D004396 | Coloring Agents |
| ID | Term |
|---|---|
| D020313 | Specialty Uses of Chemicals |
| D020164 | Chemical Actions and Uses |
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