This study aims to investigate the differences in clinical characteristics, causes of death, long-term survival, and surgical approaches between pediatric and adolescent follicular and papillary carcinoma by exploring data from the SEER database. The research is designed as a retrospective cohort study, primarily focused on collecting and comparing data to identify key disparities and outcomes between these two patient groups. It is anticipated that the findings will provide valuable insights into the management and prognosis of these cancers in younger populations, contributing to more targeted and effective treatment strategies.

This study is a retrospective cohort analysis aimed at elucidating the differences between pediatric and adolescent patients diagnosed with follicular and [specific type] carcinoma, utilizing data sourced from the SEER (Surveillance, Epidemiology, and End Results) database. The focus of the research is on a comprehensive comparison of various clinical aspects, including demographic characteristics, tumor features, treatment modalities, and survival outcomes.

Key areas of investigation include the examination of clinical characteristics such as tumor size, location, and stage at diagnosis, as well as treatment approaches including surgery types and their impact on patient outcomes. Additionally, the study will assess the causes of death and overall survival rates among these young patients, aiming to identify any significant prognostic factors.

By leveraging the robust and extensive data available in the SEER database, this study seeks to uncover critical insights into the management of follicular and [specific type] carcinoma in pediatric and adolescent populations. The findings are expected to contribute to the development of more tailored and effective therapeutic strategies, ultimately improving long-term survival and quality of life for affected patients.

Inclusion Criteria:

• Pathologically confirmed diagnosis of Follicular Thyroid Carcinoma (FTC) or Papillary Thyroid Carcinoma (PTC).
• Age range: Pediatric and adolescent patients (ages 1-18 years).

Exclusion Criteria:

• Patients with incomplete survival and clinical information.

The study population consists of pediatric and adolescent patients, aged 1 to 18 years, who have been diagnosed with Follicular Thyroid Carcinoma (FTC) or Papillary Thyroid Carcinoma (PTC). These patients were identified from a comprehensive database containing clinical, pathological, and surgical records.The population spans a diverse demographic, representing various ethnicities, genders, and geographical locations. This cohort was selected to ensure a thorough investigation of the differences in clinical presentations, surgical outcomes, and prognostic factors between the two types of thyroid carcinoma within the pediatric and adolescent age groups.

Yes, individual participant data (IPD) will be made available to other researchers under a formal data-sharing agreement.

Data will be available beginning 6 months after publication of the main study results and will be accessible for a period of 2 years.

Researchers seeking access to the IPD must submit a methodologically sound proposal. Requests should be directed to the principal investigator and will be evaluated on the basis of scientific merit and ethical considerations.