Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy

Modified Deep Lateral Wall Decompression and/or Deep Medial Wall Decompression for Moderate-to-severe Grave's Ophthalmopathy: a Prospective Study

To investigate the efficacy and safety of modified deep lateral wall decompression and/or medial wall decompression for Moderate-to-severe Grave's Ophthalmopathy.

The purpose of the study is to evaluate the effectiveness and complications of modified deep lateral wall decompression and medial wall decompression, in order to develop a standardized technical approach to the treatment of Moderate-to-severe Grave's Ophthalmopathy.

Inclusion Criteria:

1. EUGOGO/NOSPECS grade was moderate-to-severe thyroid associate ophthalmopathy;
2. CAS≤3 score;
3. stable thyroid function for at least 6 months;
4. able and willing to participate in clinical trials and ensure regular follow-up;

Exclusion Criteria:

1. any uncontrollable clinical problems (severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumors);
2. B-ultrasound or CT, MRI found other diseases causing exophthalmos (intraorbital space occupying lesion, inflammatory pseudotumor, neurofibroma, etc.);
3. uveitis, glaucoma, high myopia, diabetic retinopathy and other eye diseases
4. those who were considered by the researchers to be excluded