Postoperative Complications Following Skull Base Tumor Resection

Postoperative Complications Following Skull Base Tumor Resection: an Observational Study

The skull base tumor is located in the deep intracranial layer and is closely related to the brain stem and intracranial nerves. The incidence of postoperative complications after skull base tumor resection is high. Therefore, the perioperative management of skull base tumor resection is challenging.

1. Postoperative pulmonary complications (PPCs), always had a 11.2%-24.6% high incidence rate. Pulmonary ultrasound (LUS), as a non-invasive diagnostic tool, has high accuracy in diagnosing pulmonary complications. Compared to traditional chest X-ray examinations, pulmonary ultrasound can identify PPCs such as atelectasis and pneumothorax earlier, and it is also more accurate in diagnosing lung consolidation.With relevant literature postoperative PACU pulmonary ultrasound is used to predict the area under the PPC curve (AUC) of 0.64 in patients within 8 days after non cardiac major surgery. Through pulmonary ultrasound examination, doctors can identify high-risk patients with pulmonary complications early after surgery. In this observational study, investigators aimed to assess the occurrence of PPCs within 7 days after surgery and evaluate the accuracy of preoperative and postoperative lung ultrasound scores in predicting PPCs.
2. Patients with skull base tumors often have a high risk of postoperative lower extremity venous thrombosis due to long operation time and many postoperative complications, such as long-term bed rest. If not treated in time, lower extremity venous thrombosis can cause disability, and severe cases can cause serious consequences such as pulmonary embolism due to thrombus detachment. In this observational study, investigators aimed to prospectively collect perioperative data and the occurrence of DVT.

Inclusion Criteria:

• Age 18 and above
• American Society of Anesthesiologists physical status I to III
• Undergoing elective resection of skull base tumors
• Obtaining written informed consent

Exclusion Criteria:

• Heart failure, myocarditis, pericarditis, and cardiomyopathy
• Myocardial ischemia less than 6 months old
• Severe arrhythmia
• Severe bradycardia (heart rate below 50 beats per minute)
• Unable to complete preoperative cardiac assessment
• Severe liver dysfunction (Child Pugh C-grade)
• Severe lung diseases