Delineation of Target Volume of Stereotactic Radiotherapy for Spinal Tumors

Delineation of Target Volume of Stereotactic Radiotherapy for Spinal Tumors

The purpose of this study was to compare efficacy and side effects of two target delineation methods for stereotactic radiotherapy of metastatic spinal tumors.

The purpose of this study was to compare efficacy and side effects of two target delineation methods for stereotactic radiotherapy of metastatic spinal tumors. This is a bidirectional cohort study planned to enroll approximately 500 patients with metastatic spinal tumors. Patients are divided into two groups according to the target delineation method. Group 1：The target bolume only includes local tumor. Group 2：The target bolume includes local tumor and adjacent vertebral area.

Inclusion Criteria:

• Patients with spinal metastases or primary tumors receiving stereotactic radiotherapy;
• Patients with sufficent pre-treatment imaging data
• Patients who can cooperate with imaging review and follow-up after radiotherapy.

Exclusion Criteria:

• Patients with an expected survival of less than 3 months;
• Patients with second-course radiotherapy;
• Patients with physical conditions that cannot tolerate stereotactic radiotherapy;
• Patients with extensive spinal metastasis and no local therapeutic value