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This study aimed to assess the prevalence of psychiatric comorbidities in children and adolescents with diabetes mellitus type 1.
Assessing the impact of diabetes mellitus type 1 on quality of life. And determine the effect of associated factors on the development of psychiatric comorbidities and on quality of life in diabetes mellitus type 1.
Type 1 diabetes mellitus (TDM) is a chronic autoimmune disease. that affected carbohydrate metabolism and caused by insulin insufficiency resulting in increased blood glucose. It's one of the most common endocrine and metabolic conditions in childhood. There's 9 million people live with T1DM worldwide according to International Diabetes Federation. In Egypt, 1 in 98 families are impacted and the disease is growing at 6.7% each year. Living with T1DM has been associated with a significant impact on a person's social, mental, and psychological quality of life (QoL). as the individual must adopt blood glucose monitoring, use of injections or diabetes technology for insulin regulation, diet restrictions, and exercise. Also, there's increased risk of developing micro-and macro-vascular complications that result in morbidity and mortality in Long-term uncontrolled DM. therefore, these children and adolescents with T1DM have an increased risk of psychiatric comorbidities like depression, anxiety and sleep disorders, depression is one of the most common disorders. They appear to have a greater incidence of depression, anxiety and poor health-related quality of life (HRQoL) compared to their healthy peers. This is associated with suboptimal diabetes outcomes and better metabolic control has been found to correlate with better quality of life. This occurs especially when diagnosed at earlier age of onset, history of severe hypoglycemia and chronic hyperglycemia. There are no available studies that assess the presence of psychiatric comorbidities in T1DM in our locality.
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| Measure | Description | Time Frame |
|---|---|---|
| The prevalence of psychiatric comorbidities in children and adolescents with diabetes mellitus type 1. | This outcome will be measured using: The Kiddie-Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime (K-SADS-PL) version | 2 years |
| the prevalence of depression, anxiety and sleep disorder in children and adolescents with diabetes mellitus type 1 | this outcome will be measured using:
| 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| The impact of diabetes mellitus type 1 on quality of life. | This outcome will be measured using: Pediatric quality of life inventory 4.0 genetic Core scale. | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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Children and adolescent Patients with type 1 diabetes medllitus aged 8-15 years old.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Omnia Fath-Allah, Physician | Contact | +201012304476 | omnaya.16266093@med.aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Dalia Mahran | Assiut University | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38233629 | Background | Ashraf MN, Cheng AYY, Robinson DJ. Emotional, Psychological, and Social Well-being Experience of Long-Term Living with Type 1 Diabetes Mellitus: A Patient-Psychiatrist-Endocrinologist Perspective. Diabetes Ther. 2024 Feb;15(2):317-323. doi: 10.1007/s13300-023-01527-w. Epub 2024 Jan 17. | |
| 36000101 | Background |
| Label | URL |
|---|---|
| Type 1 diabetes in international diabetes Federation | View source |
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| ID | Term |
|---|---|
| D003922 | Diabetes Mellitus, Type 1 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Abouzid MR, Ali K, Elkhawas I, Elshafei SM. An Overview of Diabetes Mellitus in Egypt and the Significance of Integrating Preventive Cardiology in Diabetes Management. Cureus. 2022 Jul 20;14(7):e27066. doi: 10.7759/cureus.27066. eCollection 2022 Jul. |
| 24637304 | Background | El-Ziny MA, Salem NA, El-Hawary AK, Chalaby NM, Elsharkawy AA. Epidemiology of childhood type 1 diabetes mellitus in Nile Delta, northern Egypt - a retrospective study. J Clin Res Pediatr Endocrinol. 2014;6(1):9-15. doi: 10.4274/Jcrpe.1171. |
| Type 1 diabetes index | View source |
| Psychological care of children and adolescents with type 1 diabetes | View source |
| Evaluation of psychological characteristics of Turkish children with type 1 diabetes mellitus from two demographically and geographically distinct regions | View source |
| The cognitive and psychological effects of living with type 1 diabetes | View source |
| High Rate of Depression among Saudi Children with Type 1 Diabetes | View source |
| Updating and validation of the socioeconomic status scale for health research in Egypt | View source |
| Type 1 Diabetes | View source |
| Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data | View source |
| Children's Depression Inventory 2nd Edition | View source |
| A measure of anxiety symptoms among children | View source |
| CHILDREN'S SLEEP HABITS QUESTIONNAIRE (ABBREVIATED) | View source |
| The PedsQL 4.0 Generic Core Scales: | View source |
| D004700 | Endocrine System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |