A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease (AD) with moderate to severe psychosis related to AD.
Inclusion Criteria
Exclusion Criteria
- Patients will not be able to participate if they have:
i) Psychotic symptoms that are primarily attributable to a condition other than the AD causing the dementia, eg, schizophrenia, schizoaffective disorder, delusional disorder, or mood disorder with psychotic features.
ii) History of major depressive episode with psychotic features during the 12 months prior to Screening, or history of bipolar disorder, schizophrenia, or schizoaffective disorder.
iii) Patients are not able to participate if they have certain safety concerns, including certain laboratory test irregularities.
* Other protocol-defined Inclusion/Exclusion criteria apply.
Clinical.Trials@bms.com855-907-3286
Gilbert, Arizona 85297, United States
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Los Angeles, California 90033-5313, United States
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Bloomfield Township, Michigan 48302-1909, United States
St Louis, Missouri 63128, United States
Toms River, New Jersey 08755, United States
Greensboro, North Carolina 27410-3311, United States
Providence, Rhode Island 02903, United States
San Antonio, Texas 78229-3901, United States
Ciudad Autónoma de Buenos Aires, Buenos Aires 1056, Argentina
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