Mindfulness Approach for Reducing Anxiety and Gloom in Ocular Inflammatory Diseases

Effects of a Digital Mindfulness and Meditation Intervention on Mental Health and Vision-Related Quality of Life in Adults With Non-infectious Uveitis

The proposed study is a block-randomized, controlled trial to evaluate the effects of a digital meditation and mindfulness practice on mental health in patients with non-infectious uveitis.

Non-infectious uveitis is an immune-mediated inflammatory disease of the eye that can occur alone or be associated with other autoimmune diseases. This chronic condition can be isolating and complex for patients to manage, leading to increased rates of anxiety and depression symptoms in uveitis patients compared to the general population.

In collaboration with Calm Health, the investigators aim to evaluate the efficacy of Calm Health's meditation, mindfulness, and clinical programs in reducing symptoms of anxiety and depression, as well as perceived stress, in patients. Overall, the investigators aim to collect data on the value of supplementing medical care with an accessible digital mental health resource.

Inclusion Criteria:

• Is 18 or older at time of enrollment.
• Is willing to download Calm Health on their smartphone
• Is able to operate a smartphone & Calm Health without assistance
• Is able to read words on a screen without assistance
• Diagnosis of non-infectious uveitis

Exclusion Criteria:

• Is under 18 at time of enrollment.
• Has started taking a new anti-depressant, anti-anxiety, or other psychiatric medication to improve mood within the past month.
• Plans to start taking a new anti-depressant, anti-anxiety, or other psychiatric medication to improve mood in the next 12 weeks.
• Has started any type of psychotherapy within the past 3 months.
• Plans to start any type of psychotherapy within the next 12 weeks.
• Already has a mindfulness/meditation app on their smartphone.
• Is unable to operate a smartphone or read words on a screen without assistance.
• Is unable or unwilling to download the Calm Health app on their smartphone.
• Does not consent to their anonymized data being collected via Calm Health app.