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To find out if the percentage of endometrial compaction is correlated to clinical pregnancy rate in down regulated frozen embryo transfer cycle. Endometrial compaction is the change in endometrial thickness between the end of the estrogen only phase and the day of embryo transfer. In concept, the compaction of the endometrium after progesterone initiation indicates that the endometrium is responsive to progesterone and could therefore be used as a proxy for endometrial receptivity predictability of FET cycle outcome
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Infertility patients planning for FET |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational | Drug | To observe if endometrial compaction ≥ 5% in down regulated FET cycles increases clinical pregnancy rate. |
|
| Measure | Description | Time Frame |
|---|---|---|
| clinical pregnancy rate | Clinical pregnancy rate, determined by visualizing a viable embryo within the uterine cavity by ultrasound 3-4 weeks after ET, in patients with endometrial compaction in down regulated FET cycles in comparison to non endometrial compaction. | 3-4 wks after ET |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of change of endometrial thickness between the end of estrogen administration only phase and the day of embryo transfer. | 3-4 wks after ET | |
| Chemical pregnancy rates, detected by positive hCG test in the absence of pregnancy findings on TVUS |
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Inclusion Criteria:
Exclusion Criteria:
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Infertility patients planning for FET
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams University | Recruiting | Cairo | Egypt |
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| ID | Term |
|---|---|
| D057832 | Watchful Waiting |
| ID | Term |
|---|---|
| D017063 | Outcome Assessment, Health Care |
| D010043 | Outcome and Process Assessment, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
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| 3-4 wks after ET |
| Number of estrogen administration days | 10 days before ET |