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In Belgium, various structures and reimbursement programs are in place for managing Type 2 Diabetes Mellitus (T2DM). The Diabetes Care Trajectory is primarily utilized for patients who require a maximum of two insulin injections per day. In contrast, patients needing multiple daily insulin injections are managed under a diabetes convention program.
The Diabetes Care Trajectory has been operational since 2009. However, unlike patients in the diabetes convention program, where the profile and quality of care are regularly audited, there is limited information available regarding the profile and outcomes of patients within the Care Trajectory. This retrospective study aims to compare the profiles, including complications and quality of care, of T2DM patients across both groups.
This retrospective study will collect data from T2DM patients enrolled in either the Diabetes Care Trajectory or the diabetes convention program. The data gathered will encompass quality of care, clinical status, complications, and metabolic state.
The profiles of these patient populations will be compared cross-sectionally for each year within the study period (2009-2024). Additionally, a longitudinal analysis will be conducted to examine the evolution of these profiles over the entire study period. Data will be extracted from electronic case records maintained at participating sites across Belgium.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The Diabetes Care trajectory | The care trajectory is designed for individuals with T2DM who are treated with Glucagon-like peptide-1 (GLP-1) analogs (injectable or oral) or require 1 to 2 insulin injections per day. It can also be initiated when blood sugar-lowering medication (pills) is no longer sufficient and the use of a GLP-1 analog or insulin is being considered. The follow-up and management is mainly being taken care of by general practioners, with minor follow-up in specialised diabetes centers. |
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| The Diabetes Convention | The Diabetes Convention is intended for individuals with T2DM who require specialized care due to the complexity of their insulin treatment (multiple daily insulin injections). Specialised diabetes centers in (university) hospitals are responsible for providing comprehensive follow-up and management of these patients. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Follow-up in the Diabetes Care Trajectory | Other | Being followed-up in the Diabetes Care Trajectory in Belgium |
|
| Measure | Description | Time Frame |
|---|---|---|
| HbA1c | Glycated haemoglobin A1c | Yearly for the entire study period (2009 - 2024) |
| Measure | Description | Time Frame |
|---|---|---|
| Complications of diabetes | Number of diabetes-associated complications such as retinopathy, nephropathy and macroangiopathy. | Yearly for the entire study period (2009 - 2024) |
| Cholesterol profile |
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Inclusion Criteria:
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T2DM patients being followed up in the Diabetes Care Trajectory or in the Diabetes Convention (group B) in Belgium
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Astrid Lavens | Contact | 0032 2 642 57 82 | astrid.lavens@kuleuven.be | |
| Lisa Van Ryckeghem, PhD | Contact | 003216342129 | CSM.endocrino@uzleuven.be |
| Name | Affiliation | Role |
|---|---|---|
| Chantal Mathieu, MD,pHD | Universitaire Ziekenhuizen KU Leuven | Principal Investigator |
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Follow-up in the Diabetes Convention | Other | Being followed-up in the Diabetes Convention in Belgium |
|
Total levels of cholesterol
| Yearly for the entire study period (2009 - 2024) |
| Insulin requirements | The need for insulin (units) on a daily basis | Yearly for the entire study period (2009 - 2024) |
| D004700 | Endocrine System Diseases |