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The purpose of this study is to compare the amount of RAY1225 that gets into the blood stream and how long it takes the body to get rid of it, when injected under the skin of the upper arm and thigh compared to the abdomen. The study will be conducted in healthy males and females with different body sizes. The tolerability of RAY1225 will be evaluated and information about any side effects experienced will be collected. For each participant, the study will last about 7 weeks, including screening.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| RAY1225 - Upper Arm | Experimental | Participants received 3mg RAY1225 by subcutaneous injection on upper arm. |
|
| RAY1225 - Thigh | Experimental | Participants received 3mg RAY1225 by subcutaneous injection on thigh. |
|
| RAY1225 - Abdomen | Experimental | Participants received 3mg RAY1225 by subcutaneous injection on abdomen. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| RAY1225 | Drug | administered SC |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve of RAY1225 From Time Zero to Infinity (AUC[0-∞]) | DAY1~43 | |
| PK: Maximum Concentration (Cmax) of RAY1225 | DAY1~43 |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with adverse events | DAY1~43 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guangdong Hospital of Chinese Medicine | Guanzhou | Guangdong | China |
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