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Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and radiological examination (assessment carious, periodontal, mucosal and functional), which is part of the routine assessment in the service of odontology from Toulouse University Hospital.
Saliva and subgingival plaque samples, classically carried out in routine dental surgery as part of the health check-up oral, will be used to carry out bacterial assays.
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and radiological examination (assessment carious, periodontal, mucosal and functional), which is part of the routine assessment in the service of odontology from Toulouse University Hospital.
As part of the health check-up oral, Will be taken:
A collection of the history and disease risk factors will then be carried out. periodontal problems (stress level assessed using the visual analogue scale, history personal and family periodontal diseases, oral hygiene habits, etc.) by a routine care interview, the clinical examination (visual examination and recording of oral and periodontal) and radiological examination.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| biological sampling | Other | As part of the health check-up oral, Will be taken:
|
| Measure | Description | Time Frame |
|---|---|---|
| average quantity of Porphyromonas gingivalis | estimate the average quantity of Porphyromonas gingivalis (Pg) in saliva patients who have had recurrent miscarriages (3 consecutive miscarriages < 14 weeks of amenorrhea) | AT INCLUSION = T0 |
| Measure | Description | Time Frame |
|---|---|---|
| microbiological composition | microbiological composition of the saliva in women having had repeated miscarriages : Salivary samples by sputum (1 per patient). The patient will retain her saliva for 1 minute in the mouth and it will be collected in a sterile bottle (approximately 5 ml). | AT INCLUSION = T0 |
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Inclusion Criteria:
Exclusion Criteria:
women whom had repeated miscarriages
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women whom had repeated miscarriages : at least 3
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| alexia VINEL, md | Contact | +33 5 61 32 25 09 | vinel.a@chu-toulouse.fr | |
| stephanie brayer | Contact | +33 5 61 32 25 09 | Brayer.Stephanie@iuct-oncopole.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UH Toulouse | Recruiting | Toulouse | France |
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| ID | Term |
|---|---|
| D000022 | Abortion, Spontaneous |
| D004368 | Dry Socket |
| ID | Term |
|---|---|
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D009059 | Mouth Diseases |
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| microbiological composition |
microbiological composition of the subgingival plaque in women having had repeated miscarriages Samples of subgingival plaque in the periodontal sulcus (assessed during periodontal probing) using sterile paper points (minimum 3 and maximum 10 per patient) inserted for 30 seconds into the periodontal sulcus then put in a tube sterile. The plate collection is done by capillary action on the paper tip, a very small quantity is thus taken. |
| AT INCLUSION = T0 |
| D009057 | Stomatognathic Diseases |