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Associative Peripheral Stimulation (APS) is a non-invasive therapy intended for stroke rehabilitation involving transcutaneous electrical muscle stimulation paired with voluntary movement. This pilot study investigates whether APS applied during the acute phase of stroke recovery may reduce impairment and improve function in the affected upper extremity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Experimental | Treatment |
|
| Group B | Active Comparator | Control |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Associative Peripheral Stimulation (APS) 1.0 | Device | Associative peripheral stimulation paired with rehabilitative exercises. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maximum Average of Range of Motion (ROM) | Measure of distal extensor function (wrist and fingers). Unit of measurement: degrees (°). Higher scores indicate better outcomes. | 5 weeks |
| Fugl-Meyer Assessment Upper-Extremity (FMA-UE) | Measure of motor recovery in stroke patients with hemiparesis. Scoring range: 0 to 66. Higher scores indicate better outcomes. | 5 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum Average of Range of Motion (ROM) | Measure of distal extensor function (wrist and fingers). Unit of measurement: degrees (°). Higher scores indicate better outcomes. | 3 months |
| Fugl-Meyer Assessment Upper-Extremity (FMA-UE) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed A Rahim, MTM | Contact | +1 (916) 825-8792 | ahmed.rahim@alumni.ucsf.edu |
| Name | Affiliation | Role |
|---|---|---|
| Daniel San Juan Orta, MD | National Institute of Neurology & Neurosurgery | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| General Hospital of Mexico | Recruiting | Mexico City | Mexico |
Individual participant data shall not be made available to other researchers.
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| Peripheral Neuromuscular Stimulation | Device | Random peripheral stimulation paired with rehabilitative exercises. |
|
Measure of motor recovery in stroke patients with hemiparesis. Scoring range: 0 to 66. Higher scores indicate better outcomes.
| 3 months |
| Action Research Arm Test (ARAT) | Measure of four functional domains: grasp, grip, pinch, and gross arm movement. Scoring Range: 0 to 57. Higher scores indicate better outcomes. | 5 weeks |
| Action Research Arm Test (ARAT) | Measure of four functional domains: grasp, grip, pinch, and gross arm movement. Scoring Range: 0 to 57. Higher scores indicate better outcomes. | 3 months |
| La Raza National Medical Center | Recruiting | Mexico City | Mexico |
|
| National Institute of Neurology & Neurosurgery | Recruiting | Mexico City | Mexico |
|
| ID | Term |
|---|---|
| D020521 | Stroke |
| D000083242 | Ischemic Stroke |
| D000083302 | Hemorrhagic Stroke |
| D010291 | Paresis |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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