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The goal of this clinical trial is to learn the differences severity level of diabetic neuropathy based on electromyelography in type II diabetic patient with and without comorbidities. The main questions of this study:
Researchers will collect information based on hospital registry as secondary data of in type II diabetic patient with and without comorbidities. The data consist of demographic data, clinical presentation, laboratory, and electromyography were collected from hospital registry by reviewing medical record. Then, the data was analyzed by using IBM SPSS Statistics v26.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Type II Diabetic Mellitus without comorbidities | Patient who suffered diabetic neuropathy and history of type II diabetic mellitus without comorbidities |
| |
| Type II Diabetic Mellitus with hypertension | Patient who suffered diabetic neuropathy and history of type II diabetic mellitus with hypertension |
| |
| Type II Diabetic Mellitus with hypertension and dyslipidemia | Patient who suffered diabetic neuropathy and history of type II diabetic mellitus with hypertension and dyslipidemia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electromyography | Diagnostic Test | All of groups will have assessment of electromyography result |
|
| Measure | Description | Time Frame |
|---|---|---|
| Distal Latency | Distal latency defined as time between stimuli until deflection of Compound Muscle Action Potentials (CMAP) from baseline | Electromyography examination was done approximately 1 year after clinical onset of neuropathy appear |
| Measure | Description | Time Frame |
|---|---|---|
| Nerve Conduction Velocity | Nerve Conduction Velocity defined as the measurement of axon conduction velocity by dividing space of nerve conduction with time needed | Electromyography examination was done approximately 1 year after clinical onset of neuropathy appear |
| Amplitude |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with type II diabetic mellitus who suffered diabetic neuropathy which diagnosed by using electromyography and fulfill the eligibility criteria
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dr. Kariadi Central General Hospital | Semarang | Central of Java | Indonesia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33194943 | Background | Lu Y, Xing P, Cai X, Luo D, Li R, Lloyd C, Sartorius N, Li M. Prevalence and Risk Factors for Diabetic Peripheral Neuropathy in Type 2 Diabetic Patients From 14 Countries: Estimates of the INTERPRET-DD Study. Front Public Health. 2020 Oct 20;8:534372. doi: 10.3389/fpubh.2020.534372. eCollection 2020. | |
| 15668414 | Background |
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| ID | Term |
|---|---|
| D003929 | Diabetic Neuropathies |
| ID | Term |
|---|---|
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D048909 | Diabetes Complications |
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| ID | Term |
|---|---|
| D004576 | Electromyography |
| ID | Term |
|---|---|
| D004568 | Electrodiagnosis |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D009213 | Myography |
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Amplitude define as the height of first negative deflection of Compound Muscle Action Potentials (CMAP) from baseline |
| Electromyography examination was done approximately 1 year after clinical onset of neuropathy appear |
| England JD, Gronseth GS, Franklin G, Miller RG, Asbury AK, Carter GT, Cohen JA, Fisher MA, Howard JF, Kinsella LJ, Latov N, Lewis RA, Low PA, Sumner AJ; American Academy of Neurology; American Association of Electrodiagnostic Medicine; American Academy of Physical Medicine and Rehabilitation. Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. Neurology. 2005 Jan 25;64(2):199-207. doi: 10.1212/01.WNL.0000149522.32823.EA. |
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |