Platelet Rich Plasma Combined With Platelet Rich Fibrin i... | NCT06573502

Studies
Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis

NCT06573502

Sponsor

Aliaa Babekir Ahmed Mohamed

Status

Completed

Last Update Posted

Dec 12, 2025Actual

Enrollment

42Actual

Phase

Not Applicable

Conditions

Osteoarthritis

Interventions

Prp with prf or prp or prf

Countries

Egypt

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Dec 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Mar 29, 2025Actual

Primary Completion Date

Sep 29, 2025Actual

Completion Date

Nov 16, 2025Actual

First Submitted Date

Jul 31, 2024

First Submission Date that Met QC Criteria

Aug 23, 2024

First Posted Date

Aug 27, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Dec 5, 2025

Last Update Posted Date

Dec 12, 2025Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Studying effectiveness of prp with prf comparing with prp or prf for mangement of tmj osteoarthritis as result in pain and mandibular movement in adult pt

Detailed Description

45 pt assigned for the study , divided in to three gruops to comparing new combination of prp with prf in management of TMJ OA

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

42Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
prp with prf group	Experimental	Pt will recievd prp with prf	Combination Product: Prp with prf or prp or prf
prp group	Active Comparator	Pt will recieve prp only	Combination Product: Prp with prf or prp or prf
prf group	Experimental	Pt will recieve prf only	Combination Product: Prp with prf or prp or prf

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Prp with prf or prp or prf	Combination Product	Combination	prf group prp group prp with prf group

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Pain severty	Visual analog scale measure for pain most sever pain take 10 minimum pain take 0	6 months

Secondary Outcomes

Measure	Description	Time Frame
Maximum mouth opening	Measured with calipar	6 months

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Adult pt with OA

Exclusion Criteria:

Medicaly compromised

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Hassan Ab Ghany, Prof	Cairo University	Study Director

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Cairo university		Cairo			Egypt

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D010003	Osteoarthritis

Ancestor Terms

ID	Term
D001168	Arthritis
D007592	Joint Diseases
D009140	Musculoskeletal Diseases
D012216	Rheumatic Diseases

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D051219	Pituitary Adenylate Cyclase-Activating Polypeptide
D056690	Prolactin-Releasing Hormone

Ancestor Terms

ID	Term
D009414	Nerve Growth Factors
D036341	Intercellular Signaling Peptides and Proteins
D010455	Peptides
D000602	Amino Acids, Peptides, and Proteins

Browse Leaves

Not provided

Browse Branches

Not provided