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Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound. A cuirass for extrathoracal negative pressure ventilation is placed onto the chest but not switched on. During usual positive pressure ventilation a ventilatory, a hemodynamic and a 3D full volume ultrasounddataset of the right and left ventricle is recorded and severity of tricuspidal regurgitation examined. Afterwards negative pressure ventilation is started and positive pressure ventilation reduced as far as possible without reduction of tidal volumes. The same dataset of ventilation, hemodynamics and ultrasound is collected again during negative pressure ventilation. Afterwards the cuirass gets removed, study finished and everything proceeds as during standard procedure.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Negative Pressure Ventilation | Device | Substitution of positive pressure ventilation by negative pressure ventilation |
| Measure | Description | Time Frame |
|---|---|---|
| stroke volume index | transesophageal ultrasound measurement | 1 minute |
| Measure | Description | Time Frame |
|---|---|---|
| RVEF | transesophageal ultrasound measurement | 1 minute |
| LVEF | transesophageal ultrasound measurement | 1 minute |
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Inclusion Criteria:
Exclusion Criteria:
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All patients for tricuspidal clipping without an exclusion criterium
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinikum Karlsburg, Klinik für Anästhesiologie | Karlsburg | Mecklenburg-Vorpommern | 17495 | Germany |
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| ID | Term |
|---|---|
| D018497 | Ventricular Dysfunction, Right |
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D018754 | Ventricular Dysfunction |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| volumes of chambers | transesophageal ultrasound measurement | 1 minute |
| strain | transesophageal ultrasound measurement | 1 minute |
| VC | transesophageal ultrasound measurement | 1 minute |
| PISA | transesophageal ultrasound measurement | 1 minute |
| EROA | transesophageal ultrasound measurement | 1 minute |
| area of regurgitation of tricuspid valve | transesophageal ultrasound measurement | 1 minute |
| arterial blood pressures | hemodynamic measurements | 1 minute |
| venous blood pressures | hemodynamic measurements | 1 minute |
| pulmonal blood pressures | hemodynamic measurements | 1 minute |
| heart frequency | hemodynamic measurements | 1 minute |
| tidal volume | ventilatory measurements | 1 minute |
| minute volume | ventilatory measurements | 1 minute |
| breathing rate | ventilatory measurements | 1 minute |
| etCO2 | ventilatory measurements | 1 minute |
| pO2 in the blood | blood gases | 1 minute |
| pCO2 in the blood | blood gases | 1 minute |
| Laktat | blood gases | 1 minute |
| cerebral oximetry | NIRS | 1 minute |