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This study aims to compare between High tone power therapy (modulated frequency current) and Transcutaneous electrical nerve stimulation (fixed frequency current) on spasticity and selected kinematic gait parameters in stroke patients.
Stroke is a neurological deficit attributed to an acute focal injury of the central nervous system (CNS) by a vascular cause . Stroke is one of the leading causes of disability and mortality in the globe, stroke occurs when blood flow to the brain is restricted due to a blocked or ruptured artery; the cerebral energy supply is interrupted, resulting in tissue destruction and widespread neuronal, cognitive impairments, and psychological morbidity .
Stroke is the second major cause of death and disability worldwide with over 13 million new cases annually . Stroke has been described as a major source of both mortality and global disability . Approximately 795,000 people experience stroke annually, and 60% (or 465,000) of them need rehabilitation .
Spasticity is a symptom of stroke, brain and spinal cord damage, multiple sclerosis, cerebral palsy, and other neurological illnesses that cause paralysis . The most common spastic pattern in the lower limbs is adduction and extension of the knee with an Equinovarus foot . This impacts gait patterns and daily functioning activities .
Treatment modalities for the management of spasticity include Stretching, splinting, Neuromuscular electrical stimulation (NMES), extracorporeal shock wave therapy, transcranial and spinal cord magnetic stimulation, Surgical treatment, neurectomy, rhizotomy, and myelotomy; also, many drugs used for treating spasticity oral drugs like Baclofen, Tizanidine, and injectable medications like Phenol/alcohol and Botulinum 2 toxin .
Transcutaneous electrical nerve stimulation (TENS) stimulates large diameter mechano-sensitive nerve fibers in the skin it's a non-invasive treatment that has been reported to affect pain control and sensory stimulation which is commonly used in the treatment of chronic and acute pain with possible mechanisms of action including segmental inhibition, the release of endogenous opioids, counter-irritation, nerve conduction block, increase muscle power and movement function .
High-tone power therapy (HTT) is a unique characteristic of electrotherapy. It uses intermediate frequency, metal-compatible alternating current whose frequency oscillates between approximately 4000 Hz and 33000 Hz, and intensity is adjusted, unlike traditional electrotherapies as transcutaneous electrical nerve stimulation (TENS). Its main effects are introducing energy into the body to activate cells, producing an oscillation or vibration in the cells and tissues to promote metabolism, scattering the mediators of pain and inflammation leading to pain relief, and normalizing cell metabolism and nerve regeneration ).
The effective management of spasticity continues to pose challenges to physiotherapy management, there appears to be a dearth of adequate information on high tone power therapy in the management of spasticity; There are several physiotherapy approaches for managing spasticity but there is a lack of evidence to show which is most effective .
Statement of the problem:
This study will answer the following question: Is there any difference between the effect of high-tone power therapy (modulated frequency current) versus transcutaneous electrical nerve stimulation (fixed frequency current) on spasticity and selected kinematic gait parameters in stroke patients?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The control group | Active Comparator | 15 patients: receiving 36 sessions of selected physical therapy program for 1 hour 3 times per week for 3 months. |
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| The study group1 | Experimental | 15 patients: receiving 36 sessions of High tone power therapy program for 30 minutes and selected physical therapy program for 30 minutes 3 times per week for 3 months (total session: 1 hour). |
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| The study group 2 | Experimental | 15 patients: receiving 36 sessions of TENS program for 30 minutes and selected physical therapy program for 30 minutes 3 times per week for 3 months (total session: 1 hour). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| high tone power therapy | Device | sessions are applied for 30 minutes, 3 times per week, for 3 months |
|
| Measure | Description | Time Frame |
|---|---|---|
| Modified Ashworth Scale (MAS) | This scale is used to measure spasticity of Calf muscle in grades from 0 to 5. | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| Computerized electromyography (EMG) using H/M ratio | EMG is an objective device used to measure spasticity of the Soleus muscle in percentage (%) | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| Ten-meter Walk test(10-MWT) | This scale is used to measure walking speed in m/s
| measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| Time up and go test (TUG) | This test is used to measure time taken by patient to apply sit to stand, walk a distance of 3 meters, turn and walk back to the chair in (sec.) | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| Gait velocity | Gait Analyzer Smart Phone Application is an objective tool that assesses gait velocity (m/s). | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| cadence | Gait Analyzer Smart Phone Application is an objective tool that assesses cadence: the number of steps per second in (steps/ s). |
| Measure | Description | Time Frame |
|---|---|---|
| Lafayette Hand-held Dynamometer | This is an objective device used to measure the isometric contraction of dorsi flexors in pounds (lbs.) | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eman S Fayiz, Professor | Cairo University | Study Chair |
| Mahmoud Y El-Zanaty | Cairo University | Study Chair |
| Sandraa M Ahmed, Professor | Cairo University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| faculty of physical therapy, Cairo university | Giza | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41721793 | Derived | Mahmoud JM, Fayez ES, Ahmed S, Gelany FM, Hassan IM, El-Zanaty MY. Impact of High Tone Power Therapy on Lower Limb Spasticity and Gait Speed in Patients at Least Six Months Post-Stroke: A Randomized Controlled Trial. Physiother Res Int. 2026 Apr;31(2):e70175. doi: 10.1002/pri.70175. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D004561 | Transcutaneous Electric Nerve Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |
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Randomized controlled trial (RCT). True experimental research design study
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| transcutaneous electrical nerve stimulation (TENS) | Device | sessions are applied for 30 minutes, 3 times per week, for 3 months |
|
| selected physical therapy program | Other | sessions are applied for 1 hour, 3 times per week, for 3 months in form o fstretching exercise , range of motion exercises , conventional gait training progressive resistance exercises |
|
| measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| step time | Gait Analyzer Smart Phone Application is an objective tool that assesses step time in ( msec.) | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| step time symmetry | Gait Analyzer Smart Phone Application is an objective tool that assesses step time symmetry: the symmetry in time between affected and unaffected lower limbs in percentage (%) | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| step length | Gait Analyzer Smart Phone Application is an objective tool that assesses step length by the inertial sensor system symmetry in meters (m). | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| step length symmetry | Gait Analyzer Smart Phone Application is an objective tool that assesses step length symmetry: the symmetry in step length between affected and unaffected lower limbs in percentage (%) | measurements will be done 3 days before the start of the treatment program and will be done after 3 days post intervention |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D000698 |
| Analgesia |
| D000760 | Anesthesia and Analgesia |