Botulinum Toxin and Mesotherapy on Enhancement of Facial Scarring

Botulinum Toxin Versus Mesotherapy on Enhancement of Facial Scarring (A Randomized Controlled Clinical Trial)

Most of the body's tissues can undergo wound repair following a disruption of tissue integrity. Upon healing, these wounds result in scar formation. The scars widen when the overlying musculature pulls apart suture lines. Botulinum Toxin A (BTA) is known to prevent fibroblast proliferation and it also induces temporary muscle paralysis. Also, mesotherapy is the non-invasive transdermal injection which can aid the skin to increase collagen and elastin production. Thus, both techniques are eligible for enhancement of facial scars.

Inclusion Criteria:

• Patient suffering from vertical or oblique forehead lacerations caused by trauma.
• Recent and fresh wounds.
• Atrophic scar (linear scar).

Exclusion Criteria:

• Infected wound.
• Patient on chemotherapy treatment and history of malignancy.
• Patients suffering from burns on the forehead or complicated lacerations.
• Allergy to drugs used in this study