A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent... | NCT06561386 | Trialant

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent... | NCT06561386 | Trialant

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Eligibility Criteria: Inclusion Criteria

Participants must have histologically confirmed Stage IV or recurrent Non-small Cell Lung Cancer (NSCLC) of non-squamous (NSQ) histology with no prior systemic anti-cancer therapy given as primary therapy for advanced or metastatic disease.

Participants must have measurable PD-L1 ≥ 1% Tumor Cell (TC) score by the investigational PD-L1 immunohistochemistry (IHC) assay VENTANA PD-L1 (SP263) CDx Assay conducted by central laboratory during the screening period prior to randomization.

Participants must have measurable disease by computed tomography (CT) or magnetic resonance imaging (MRI) per RECIST v1.1 criteria.

Participants must have an Easter Cooperative Oncology Group (ECOG) performance status of ≤ 1 at screening.

Participants must have a life expectancy of at least 3 months at the time of randomization.

Exclusion Criteria

Participants must not be pregnant and/or breastfeeding.

Participants with epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), or ROS-1 mutations that are sensitive to available targeted inhibitor therapy. Participants with unknown EGFR, ALK, or ROS-1 status are excluded.

Participants with known BRAFV600E mutations, that are sensitive to available targeted inhibitor therapy; participants with known activating rearranged during transfection (RET) mutations or neurotrophic tyrosine receptor kinase (NTRK) fusion gene alterations are excluded. Participants with unknown or indeterminate BRAF mutation, activating RET mutations or NTRK fusion gene alterations are eligible.

Participants must not have untreated central nervous system (CNS) metastases.

Participants must not have leptomeningeal metastases (carcinomatous meningitis).

Participants must not have concurrent malignancy requiring treatment.

Participants must not have an active autoimmune disease.

Participants must not have history of interstitial lung disease or pneumonitis that required oral or intravenous (IV) glucocorticoids to assist with management.

Participants must not have a history of myocarditis.

Participants must not have had prior treatment with an anti-PD-1, anti-PD-L1, anti-PD-L2, or anti-CTLA-4 antibody, or other antibody or drug targeting T-cell co-stimulation or checkpoint pathways.

Other protocol-defined Inclusion/Exclusion criteria apply.

Local Institution - 0487Not yet recruiting

Mobile, Alabama 36604, United States

Site 0487Contact

Southern Arizona VA Health Care SystemRecruiting

Tucson, Arizona 85723, United States

Local Institution - 0112Withdrawn

Los Angeles, California 90404, United States

University of California Davis (UC Davis) Comprehensive Cancer CenterRecruiting

Sacramento, California 95817, United States

San Francisco Oncology AssociatesRecruiting

San Francisco, California 94115, United States

UCLA Hematology/Oncology - Santa MonicaRecruiting

Santa Monica, California 90404, United States

Local Institution - 0500Not yet recruiting

Grand Junction, Colorado 81501, United States

Local Institution - 0472Not yet recruiting

Westminster, Colorado 80023, United States

University of Miami Hospital and Clinics, Sylvester Cancer CenterRecruiting

Miami, Florida 33136, United States

Memorial Hospital WestRecruiting

Pembroke Pines, Florida 33028, United States

Florida Cancer Specialists - NorthRecruiting

St. Petersburg, Florida 33705, United States

Local Institution - 0477Not yet recruiting

Tamarac, Florida 33321, United States

Florida Cancer Specialists - EastRecruiting

West Palm Beach, Florida 33401, United States

Local Institution - 0509Not yet recruiting

Coeur d'Alene, Idaho 83815, United States

Affiliated Oncologists, LLCRecruiting

Chicago Ridge, Illinois 60415, United States

Cancer Center of KansasRecruiting

Wichita, Kansas 67214, United States

Saint Elizabeth Medical Center EdgewoodRecruiting

Edgewood, Kentucky 41017, United States

Baptist Health LexingtonRecruiting

Lexington, Kentucky 40503, United States

Local Institution - 0502Not yet recruiting

Paducah, Kentucky 42003, United States

Local Institution - 0505Not yet recruiting

Annapolis, Maryland 21401, United States

Local Institution - 0473Not yet recruiting

Royal Oak, Michigan 48073, United States

Hattiesburg Clinic Hematology/OncologyRecruiting

Hattiesburg, Mississippi 39401-7233, United States

Local Institution - 0498Not yet recruiting

Kansas City, Missouri 64132, United States

Local Institution - 0308Completed

Bozeman, Montana 59715, United States

Renown Regional Medical CenterRecruiting

Reno, Nevada 89502, United States

Local Institution - 0507Not yet recruiting

Morristown, New Jersey 07960, United States

Local Institution - 0346Completed

Paterson, New Jersey 07503, United States

Local Institution - 0381Completed

Albuquerque, New Mexico 87108, United States

Local Institution - 0356Active, not recruiting

Hawthorne, New York 10532, United States

Veterans Affairs New York Harbor Healthcare SystemRecruiting

New York, New York 10016, United States

Local Institution - 0380Withdrawn

Northport, New York 11768, United States

University of Rochester Medical CenterRecruiting

Rochester, New York 14642, United States

Local Institution - 0511Not yet recruiting

Schenectady, New York 12308, United States

SUNY Upstate Medical UniversityRecruiting

Syracuse, New York 13210, United States

Local Institution - 0357Withdrawn

The Bronx, New York 10468, United States

Local Institution - 0352Completed

Asheville, North Carolina 28806, United States

East Carolina UniversityRecruiting

Greenville, North Carolina 27858, United States

Local Institution - 0369Withdrawn

Canton, Ohio 44708, United States

Local Institution - 0486Not yet recruiting

Centerville, Ohio 45459, United States

University of Cincinnati Medical CenterRecruiting

Cincinnati, Ohio 45219, United States

Local Institution - 0199Completed

Cleveland, Ohio 44106, United States

Local Institution - 0366Withdrawn

Massillon, Ohio 44646, United States

Local Institution - 0512Not yet recruiting

Zanesville, Ohio 43701, United States

Lancaster General Hospital - Ann B Barshinger Cancer InstituteRecruiting

Lancaster, Pennsylvania 17601, United States

Local Institution - 0504Not yet recruiting

Philadelphia, Pennsylvania 19107, United States

Texas Oncology - West TexasRecruiting

Abilene, Texas 79606, United States

Local Institution - 0305Withdrawn

Harlingen, Texas 78550, United States

University of Texas MD Anderson Cancer CenterRecruiting

Houston, Texas 77030, United States

The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer CenterRecruiting

Tyler, Texas 75701, United States

Local Institution - 0302Not yet recruiting

Salt Lake City, Utah 84112, United States

Local Institution - 0499Not yet recruiting

Lacey, Washington 98503, United States

Local Institution - 0508Not yet recruiting

Seattle, Washington 98104, United States

Hospital Británico de Buenos AiresRecruiting

Ciudad Autónoma de Buenos Aires, Buenos Aires 1280, Argentina

Karina Vera, Site 0379Contact

1121571056

Instituto Alexander FlemingRecruiting

Ciudad Autónoma de Buenos Aires, Buenos Aires C1426ANZ, Argentina

Claudio Martin, Site 0217Contact

5491166936669

Hospital Italiano de Buenos AiresRecruiting

ABB, Buenos Aires F.D. C1199ABB, Argentina

Lorena Lupinacci, Site 0219Contact

5411495902008159

Instituto Médico Río CuartoRecruiting

Río Cuarto, Córdoba Province X5800AEV, Argentina

Local Institution - 0493Not yet recruiting

Bariloche, Río Negro Province 8400, Argentina

Sanatorio ParqueRecruiting

Rosario, Santa Fe Province S2000DSV, Argentina

Hospital Privado Universitario de CórdobaRecruiting

Córdoba, 5016, Argentina

Instituto Oncológico de CórdobaRecruiting

Córdoba, X5000HWE, Argentina

Hospital Privado de ComunidadRecruiting

Mar del Plata, 7600, Argentina

Gosford HospitalRecruiting

Gosford, New South Wales 2250, Australia

GenesisCare North ShoreRecruiting

St Leonards, New South Wales 2065, Australia

The Prince Charles HospitalRecruiting

Brisbane, Queensland 4032, Australia

Gallipoli Medical Research LtdRecruiting

Brisbane, Queensland 4120, Australia

Local Institution - 0057Not yet recruiting

Elizabeth Vale, South Australia 5112, Australia

Box Hill HospitalRecruiting

Box Hill, Victoria 3128, Australia

Fiona Stanley HospitalRecruiting

Murdoch, Western Australia 6150, Australia

St. John of God Murdoch HospitalRecruiting

Murdoch, Western Australia 6150, Australia

Universitätsklinikum KremsRecruiting

Krems, Lower Austria 3500, Austria

Klinikum Wels-Grieskirchen GmbHRecruiting

Wels, Upper Austria 4600, Austria

Klinik FloridsdorfRecruiting

Vienna, 1210, Austria

Antwerp University HospitalRecruiting

Edegem, Antwerpen 2650, Belgium

UZ BrusselRecruiting

Brussels, Bruxelles-Capitale, Région de 1090, Belgium

Jessa ZiekenhuisRecruiting

Hasselt, Limburg 3500, Belgium

Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site GodinneRecruiting

Yvoir, Namur 5530, Belgium

AZ Delta vzwRecruiting

Roeselare, West-Vlaanderen 8800, Belgium

Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart TilmanRecruiting

Liège, 4000, Belgium

PronutrirRecruiting

Fortaleza, Ceará 60810180, Brazil

Cetus Oncologia - Unidade Belo HorizonteRecruiting

Belo Horizonte, Minas Gerais 30110-022, Brazil

CTO - Centro de Tratamento OncológicoRecruiting

Belém, Pará 66063-495, Brazil

Liga Norte Riograndense Contra o CâncerRecruiting

Natal, Rio Grande do Norte 59075-740, Brazil

Hospital de Clinicas de Porto AlegreRecruiting

Porto Alegre, Rio Grande do Sul 90035-903, Brazil

Hospital São Lucas da PUCRSRecruiting

Porto Alegre, Rio Grande do Sul 90610-000, Brazil

Clínica de Neoplasias LitoralRecruiting

Itajaí, Santa Catarina 88301-220, Brazil

Local Institution - 0501Not yet recruiting

Timbó, Santa Catarina 89120000, Brazil

Fundação Pio XII - Hospital de Câncer de BarretosRecruiting

Barretos, São Paulo 14784400, Brazil

NAIC - Instituto do CâncerRecruiting

Bauru, São Paulo 17033-490, Brazil

Centro de Oncologia - CEON+ - Unidade São Caetano do SulRecruiting

São Caetano do Sul, São Paulo 09541-270, Brazil

Local Institution - 0497Not yet recruiting

Taubaté, São Paulo 12030-200, Brazil

Instituto Nacional de Câncer - INCARecruiting

Rio de Janeiro, 20231-050, Brazil

Icesp - Instituto Do Câncer Do Estado de São PauloRecruiting

São Paulo, 01246-000, Brazil

Local Institution - 0496Not yet recruiting

São Paulo, 01323001, Brazil

Local Institution - 0494Not yet recruiting

Montreal, Quebec J4B6S4, Canada

Orlandi OncologiaRecruiting

Santiago, Santiago Metropolitan 0, Chile

Fundacion Arturo Lopez Perez (FALP)Recruiting

Santiago, Santiago Metropolitan 7500921, Chile

Pontificia Universidad Catolica de ChileRecruiting

Santiago, Santiago Metropolitan 8330032, Chile

BradfordhillRecruiting

Santiago, Santiago Metropolitan 8420383, Chile

Oncocentro ApysRecruiting

Viña del Mar, Valparaiso 2520598, Chile

Local Institution - 0495Not yet recruiting

Santiago, Vitacura '7650018, Chile

Local Institution - 0182Not yet recruiting

Hefei, Anhui 230031, China

Beijing Cancer hospitalRecruiting

Beijing, Beijing Municipality 100142, China

Chongqing University Cancer HospitalRecruiting

Chongqing, Chongqing Municipality 400030, China

Chongqing Three Gorges Central HospitalRecruiting

Wanzhou, Chongqing Municipality 404000, China

Fujian Cancer HospitalRecruiting

Fuzhou, Fujian 350014, China

The First Affiliated Hospital, Sun Yat-sen UniversityRecruiting

Guangzhou, Guangdong 510080, China

The First Affiliated Hospital of Guangzhou Medical UniversityRecruiting

Guangzhou, Guangdong 510140, China

Huizhou Central People's HospitalRecruiting

Huizhou, Guangdong 516001, China

Liuzhou People's HospitalRecruiting

Liuzhou, Guangxi 545006, China

Guangxi Medical University Affiliated Tumor HospitalRecruiting

Nanning, Guangxi 530201, China

Harbin Medical University Cancer HospitalRecruiting

Harbin, Heilongjiang 150081, China

The First Affiliated Hospital of Henan Medical UniversityRecruiting

Xinxiang, Henan 453100, China

Local Institution - 0237Completed

Zhengzhou, Henan 450000, China

Local Institution - 0235Withdrawn

Wuhan, Hubei 430079, China

Hunan Cancer HospitalRecruiting

Changsha, Hunan 410013, China

First Huai'an Hospital Affiliated to Nanjing Medical UniversityRecruiting

Huai'an, Jiangsu 223300, China

The First affiliated hospital of Nanchang University (Xianghu campus)Recruiting

Nanchang, Jiangxi 330209, China

Liaoning Cancer HospitalRecruiting

Shenyang, Liaoning 110042, China

Xi'an International Medical Center HospitalRecruiting

Xi'an, Shaanxi 710126, China

Shandong Cancer HospitalRecruiting

Jinan, Shandong 250117, China

Shanghai Chest HospitalRecruiting

Shanghai, Shanghai Municipality 200030, China

Shanghai Chest HospitalRecruiting

Shanghai, Shanghai Municipality 200030, China

Zhongshan Hospital,Fudan UniversityRecruiting

Shanghai, Shanghai Municipality 200032, China

Shanxi Cancer HospitalRecruiting

Taiyuan, Shanxi 030000, China

Sichuan Cancer hospitalRecruiting

Chengdu, Sichuan 610041, China

The Second People's Hospital of NeijiangRecruiting

Neijiang, Sichuan 641000, China

Tianjin Medical University Cancer Institute & HospitalRecruiting

Tianjin, Tianjin Municipality 300060, China

The first Affiliated Hospital, Zhejiang University School of MedicineRecruiting

Hangzhou, Zhejiang 310003, China

Sir Run Run Shaw Hospital of Zhejiang University School of MedicineRecruiting

Hangzhou, Zhejiang 310016, China

Zhejiang Cancer HospitalRecruiting

Hangzhou, Zhejiang 310022, China

Taizhou Hospital of Zhejiang ProvinceRecruiting

Linhai, Zhejiang 317000, China

Guangdong Provincial People's HospitalRecruiting

Guangzhou, 510120, China

Instituto de CancerologíaRecruiting

Medellín, Antioquia 0, Colombia

Hospital Universitario San IgnacioRecruiting

Bogotá, Bogota D.C. 0, Colombia

Local Institution - 0418Not yet recruiting

Bogotá, Bogota D.C. 110131, Colombia

Local Institution - 0417Withdrawn

Valledupar, Cesar Department 200001, Colombia

Oncologos del OccidenteRecruiting

Pereira, Risaralda Department 660001, Colombia

Local Institution - 0442Not yet recruiting

Cali, Valle del Cauca Department 760032, Colombia

Local Institution - 0125Completed

Copenhagen, Capital Region 2100, Denmark

Aarhus Universitetshospital, SkejbyRecruiting

Aarhus, Central Jutland 8200, Denmark

Sygehus SoenderjyllandRecruiting

Sønderborg, Region Syddanmark 6400, Denmark

Local Institution - 0475Not yet recruiting

Dijon, Bourgogne-Franche-Comté 21000, France

CHRU de BrestRecruiting

Brest, Finistère 29200, France

CHU de Toulouse - Hopital LarreyRecruiting

Toulouse, Haute-Garonne 31059, France

Local Institution - 0092Withdrawn

Montpellier, Hérault 34298, France

Local Institution - 0093Withdrawn

Rennes, Ille-et-Vilaine 35033, France

Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de BraboisRecruiting

Vandœuvre-lès-Nancy, Meurthe-et-Moselle 54511, France

CHU Lille - Institut Coeur PoumonRecruiting

Lille, Nord 59037, France

Local Institution - 0503Not yet recruiting

Le Mans, Pays de la Loire Region 72037, France

Centre Hospitalier intercommunal de Toulon La Seyne sur MerRecruiting

Toulon, Provence-Alpes-Côte d'Azur Region 83100, France

Centre Hospitalier Lyon SudRecruiting

Pierre-Bénite, Rhône 69310, France

Local Institution - 0471Not yet recruiting

Avignon, Vaucluse 84918, France

Centre Hospitalier de la Côte BasqueRecruiting

Bayonne, 64109, France

Local Institution - 0470Not yet recruiting

Bordeaux, 33076, France

Assistance Publique Hôpitaux de Marseille - Hôpital NordRecruiting

Marseille, 13915, France

Hopitaux Universitaires Paris Centre-Hopital CochinRecruiting

Paris, 75014, France

Institut CurieRecruiting

Paris, 75248, France

Klinikum EsslingenRecruiting

Esslingen am Neckar, Baden-Wurttemberg 73730, Germany

Bundeswehrkrankenhaus UlmRecruiting

Ulm, Baden-Wurttemberg 89081, Germany

Klinikverbund AllgaeuRecruiting

Kempten (Allgäu), Bavaria 87439, Germany

Klinikum der Ludwig-Maximilians-Universitaet MuenchenRecruiting

München, Bavaria 81377, Germany

Universitätsklinikum MarburgRecruiting

Marburg, Hesse 35033, Germany

Praxis Onkologie am RaschplatzRecruiting

Hanover, Lower Saxony 30161, Germany

Local Institution - 0469Not yet recruiting

Dortmund, North Rhine-Westphalia 44263, Germany

Evangelisches Krankenhaus Herne - EickelRecruiting

Herne, North Rhine-Westphalia 44651, Germany

Universitätsklinikum Münster - Albert Schweitzer CampusRecruiting

Münster, North Rhine-Westphalia 48149, Germany

Klinikum ChemnitzRecruiting

Chemnitz, Saxony 09116, Germany

LungenClinic GrosshansdorfRecruiting

Großhansdorf, Schleswig-Holstein 22927, Germany

Local Institution - 0466Not yet recruiting

Lübeck, Schleswig-Holstein 23538, Germany

Charité Campus Virchow-KlinikumRecruiting

Berlin, 13353, Germany

Universitätsklinikum BonnRecruiting

Bonn, 53127, Germany

Universitaetsklinikum EssenRecruiting

Essen, 45122, Germany

Asklepios Klinik Gauting GmbHRecruiting

Gauting, 82131, Germany

Local Institution - 0474Not yet recruiting

Badsa, Haryana 124105, India

Site 0474Contact

Manipal HospitalsRecruiting

Bengaluru, Karnataka 560017, India

Regional Cancer Centre - ThiruvananthapuramRecruiting

Thiruvananthapuram, Kerala 695011, India

Mumbai Oncocare Centre Vile ParleRecruiting

Mumbai, Maharashtra 400 057, India

Tata Memorial HospitalRecruiting

Mumbai, Maharashtra 400012, India

All India Institute of Medical SciencesRecruiting

New Delhi, National Capital Territory of Delhi 110029, India

Local Institution - 0448Not yet recruiting

New Delhi, National Capital Territory of Delhi 110029, India

Rajiv Gandhi Cancer Institute And Research CentreRecruiting

New Delhi, National Capital Territory of Delhi 110085, India

Yashoda HospitalRecruiting

Secunderabad, Telangana 500003, India

Local Institution - 0476Not yet recruiting

Varanasi, Uttar Pradesh 221005, India

Narayana Superspecialty HospitalRecruiting

Howrah, West Bengal 711103, India

St. James's HospitalRecruiting

Dublin, D08 E9P6, Ireland

Beacon HospitalRecruiting

Dublin, D18 AK68, Ireland

Tallaght University HospitalRecruiting

Dublin, D24 NR0A, Ireland

Local Institution - 0027Withdrawn

Dublin, D9, Ireland

Instituto Tumori Giovanni Paolo IIRecruiting

Bari, Apulia 70124, Italy

Ospedale Santa Maria delle CrociRecruiting

Ravenna, Emilia-Romagna 48121, Italy

Local Institution - 0045Not yet recruiting

Monza, Lombardy 20900, Italy

ASST Grande Ospedale Metropolitano NiguardaRecruiting

Milan, Milano 20162, Italy

A.O.R.N. Ospedale dei Colli - Monaldi V.Recruiting

Naples, Napoli 80131, Italy

Azienda Ospedaliera Di Rilievo Nazionale A. CardarelliRecruiting

Naples, Napoli 80131, Italy

Istituto Nazionale Tumori Regina ElenaRecruiting

Rome, Roma 00144, Italy

Casa di Cura Dott. PederzoliRecruiting

Peschiera del Garda, Verona 37019, Italy

Local Institution - 0482Not yet recruiting

Bergamo, 24125, Italy

Local Institution - 0478Not yet recruiting

Florence, 50134, Italy

Local Institution - 0479Not yet recruiting

Palermo, 90127, Italy

Local Institution - 0222Withdrawn

Ravenna, 48121, Italy

Local Institution - 0481Not yet recruiting

Rome, 152, Italy

Local Institution - 0480Not yet recruiting

Siena, 53100, Italy

National Cancer Center Hospital EastRecruiting

Kashiwa, Chiba 277-8577, Japan

University Of Occupational And Environmental Health HospitalRecruiting

Kitakyushu, Fukuoka 807-8556, Japan

Kurume University HospitalRecruiting

Kurume, Fukuoka 830-0011, Japan

Local Institution - 0513Not yet recruiting

Gifu, Gifu 5011194, Japan

Chugoku Central HospitalRecruiting

Fukuyama-shi, Hiroshima 720-0001, Japan

Kenichi Gemba, Site 0276Contact

+81849849702121

National Hospital Organization Hokkaido Cancer CenterRecruiting

Sapporo, Hokkaido 003-0804, Japan

Local Institution - 0506Not yet recruiting

Sagamihara-Shi, Kanagawa 252-0329, Japan

Site 0506Contact

Kanagawa Cardiovascular and Respiratory CenterRecruiting

Yokohama, Kanagawa 236-0051, Japan

Kanagawa cancer centerRecruiting

Yokohama, Kanagawa 2418515, Japan

Kochi Medical School HospitalRecruiting

Nankoku, Kochi 783-8505, Japan

Local Institution - 0510Not yet recruiting

Natori-shi, Miyagi 981-1293, Japan

Sendai Kousei HospitalRecruiting

Sendai, Miyagi 9810914, Japan

Nara Medical University HospitalRecruiting

Kashihara, Nara 634-0813, Japan

Niigata Cancer Center HospitalRecruiting

Niigata, Niigata 951-8566, Japan

Kurashiki Central HospitalRecruiting

Kurashiki, Okayama-ken 710-8602, Japan

Kansai Medical University HospitalRecruiting

Hirakata, Osaka 573-1191, Japan

Kindai University HospitalRecruiting

Sakai, Osaka 590-0197, Japan

Saitama Medical University International Medical CenterRecruiting

Hidaka, Saitama 350-1298, Japan

Hamamatsu University HospitalRecruiting

Hamamatsu, Shizuoka 431-3192, Japan

Shizuoka Cancer CenterRecruiting

Nagaizumi-cho,Sunto-gun, Shizuoka 411-8777, Japan

Hirotsugu Kenmotsu, Site 0310Contact

81559895222

The Cancer Institute Hospital of JFCRRecruiting

Koto, Tokyo 135-8550, Japan

Ken Uchibori, Site 0323Contact

81335200111

Hyogo Cancer CenterRecruiting

Akashi, 6738558, Japan

Fukushima Medical UniversityRecruiting

Fukushima, 960-1295, Japan

Osaka International Cancer InstituteRecruiting

Osaka, 541-8567, Japan

Cancer Treamtent Clinic and Clinical Trials Sa de CvRecruiting

Guadalajara, Jalisco 44260, Mexico

Arké SMO S.A. de C.V.Recruiting

México, 06700, Mexico

Hospital H+ QueretaroRecruiting

Querétaro, 76000, Mexico

Centro Potosino de Investigación MédicaRecruiting

San Luis Potosí City, 78250, Mexico

Local Institution - 0030Withdrawn

Harderwijk, Gelderland 3844 DG, Netherlands

Atrium-Orbis - Zuyderland Medisch Centrum HeerlenRecruiting

Heerlen, Limburg 6419 PC, Netherlands

Local Institution - 0196Withdrawn

's-Hertogenbosch, North Brabant 5223 GZ, Netherlands

Local Institution - 0195Withdrawn

Zwolle, Overijssel 8025 AB, Netherlands

Leids Universitair Medisch CentrumRecruiting

Leiden, South Holland 2333 ZA, Netherlands

Local Institution - 0315Withdrawn

The Hague, South Holland 2512 VA, Netherlands

Ziekenhuis RijnstateRecruiting

Arnhem, 6815 AD, Netherlands

Local Institution - 0032Withdrawn

Groningen, 9700 RB, Netherlands

Local Institution - 0407Not yet recruiting

Tauranga, Bay of Plenty 3112, New Zealand

Tauranga HospitalRecruiting

Tauranga, Bay of Plenty 3112, New Zealand

Auckland City HospitalRecruiting

Auckland, 1023, New Zealand

Local Institution - 0425Not yet recruiting

Dunedin, 9016, New Zealand

Local Institution - 0406Not yet recruiting

Wellington, 6021, New Zealand

Local Institution - 0255Not yet recruiting

Konin, Greater Poland Voivodeship 62-500, Poland

Centrum Medyczne Pratia PoznańRecruiting

Poznan, Greater Poland Voivodeship 60-192, Poland

Med-Polonia Sp. z o.o.Recruiting

Poznan, Greater Poland Voivodeship 60-693, Poland

Centrum Onkologii im. Prof. Franciszka LukaszczykaRecruiting

Bydgoszcz, Kuyavian-Pomeranian Voivodeship 85-796, Poland

Local Institution - 0259Withdrawn

Warsaw, Masovian Voivodeship 04-125, Poland

Local Institution - 0257Not yet recruiting

Koszalin, West Pomeranian Voivodeship 75-581, Poland

Szpital Specjalistyczny w Prabutach Spolka z o.o.Recruiting

Prabuty, 82-550, Poland

Instytut Centrum Zdrowia Matki PolkiRecruiting

Lodz, Łódź Voivodeship 93-338, Poland

Instituto Português de Oncologia de Lisboa Francisco GentilRecruiting

Lisbon, Lisbon District 1099-023, Portugal

Unidade Local de Saúde de Coimbra, E.P.E.Recruiting

Coimbra, 3040, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil, EPERecruiting

Porto, 4200-072, Portugal

Local Institution - 0401Not yet recruiting

Porto, 4200-319, Portugal

SC Memorial Healthcare International SRLRecruiting

Bucharest, Bucharest 013812, Romania

Institutul Oncologic Bucuresti "Prof. Dr. Alexandru Trestioreanu"Recruiting

Bucharest, Bucharest 022338, Romania

SC Radiotherapy Center Cluj SRLRecruiting

Florești, Cluj 407280, Romania

Andrei Ungureanu, Site 0299Contact

40742206212

Centrul de Oncologie "Sfântul Nectarie"Recruiting

Craiova, Dolj 200542, Romania

Institutul Oncologic ClujRecruiting

Cluj-Napoca, 400015, Romania

Institutul Regional de OncologieRecruiting

Iași, 700483, Romania

Spitalul Municipal Schuller PloieștiRecruiting

Ploieşti, 100337, Romania

Local Institution - 0440Not yet recruiting

Dammam, Eastern Province 31444, Saudi Arabia

Local Institution - 0409Not yet recruiting

Jeddah, Makkah Al Mukarramah 23433, Saudi Arabia

Local Institution - 0408Not yet recruiting

Riyadh, Riyadh Region 11426, Saudi Arabia

Wits Clinical ResearchRecruiting

Soweto, Gauteng 2013, South Africa

Wits Clinical ResearchRecruiting

Johannesburg, GP 2193, South Africa

Life GroenkloofRecruiting

Pretoria, GP 0181, South Africa

Sandton Oncology Medical Group (Pty) LtdRecruiting

Sandton, GP 2196, South Africa

Cape Town Oncology TrialsRecruiting

Cape Town, Western Cape 7570, South Africa

Chungbuk National University HospitalRecruiting

Cheongju-si, Chungcheongbuk-do [Chungbuk] 28644, South Korea

Gachon University Gil Medical CenterRecruiting

Namdong-gu, Incheon-gwangyeoksi [Incheon] 21565, South Korea

Eun Kyung Cho, Site 0234Contact

82324603383

Chonnam National University Hwasun HospitalRecruiting

Hwasun, Jeonranamdo 58128, South Korea

National Cancer CenterRecruiting

Goyang-si, Kyǒnggi-do 10408, South Korea

Cha Bundang Medical Center, Cha UniversityRecruiting

Seongnam-si, Kyǒnggi-do 13496, South Korea

Pusan National University HospitalRecruiting

Busan, Pusan-Kwangyǒkshi 49241, South Korea

Local Institution - 0488Not yet recruiting

Seoul, Sejong-si 8308, South Korea

Site 0488Contact

Severance Hospital, Yonsei University Health SystemRecruiting

Seoul, Seoul-teukbyeolsi [Seoul] 03722, South Korea

Asan Medical CenterRecruiting

Seoul, Seoul-teukbyeolsi [Seoul] 05505, South Korea

Samsung Medical CenterRecruiting

Seoul, Seoul-teukbyeolsi [Seoul] 06351, South Korea

Keimyung University Dongsan HospitalRecruiting

Daegu, Taegu-Kwangyǒkshi 42601, South Korea

Local Institution - 0489Not yet recruiting

Deagu, Taegu-Kwangyǒkshi 41404, South Korea

Site 0489Contact

Local Institution - 0491Not yet recruiting

Yangsan, 50612, South Korea

CHUAC-Hospital Teresa HerreraRecruiting

A Coruña, A Coruña [La Coruña] 15006, Spain

Hospital Universitari Vall d'HebronRecruiting

Barcelona, Barcelona [Barcelona] 08035, Spain

Hospital de la Santa Creu i Sant PauRecruiting

Barcelona, Catalunya [Cataluña] 08041, Spain

Institut Català d'Oncologia - L'HospitaletRecruiting

L'Hospitalet de Llobregat, Catalunya [Cataluña] 08908, Spain

Hospital Son LlàtzerRecruiting

Palma, Illes Balears [Islas Baleares] 07198, Spain

Hospital Universitario Ramón y CajalRecruiting

Madrid, Madrid, Comunidad de 28034, Spain

Hospital Universitario 12 de OctubreRecruiting

Madrid, Madrid, Comunidad de 28041, Spain

Hospital Universitario Puerta de Hierro MajadahondaRecruiting

Majadahonda, Madrid, Comunidad de 28222, Spain

Hospital Arnau de VilanovaRecruiting

Valencia, València 46015, Spain

H.R.U Málaga - Hospital GeneralRecruiting

Málaga, 29011, Spain

Hospital Universitario Virgen Del RocioRecruiting

Seville, 41013, Spain

Local Institution - 0269Not yet recruiting

Valencia, 46026, Spain

Local Institution - 0291Not yet recruiting

Lausanne, Canton of Vaud 1011, Switzerland

Local Institution - 0341Withdrawn

Bellinzona, Canton Ticino 6500, Switzerland

Local Institution - 0290Withdrawn

Basel, 4031, Switzerland

Local Institution - 0398Withdrawn

Münsterlingen, 8596, Switzerland

Chang Gung Memorial Hospital at KaohsiungRecruiting

Kaohsiung Niao Sung Dist, Kaohsiung 83301, Taiwan

Chin-Chou Wang, Site 0445Contact

88677317123

Taipei Medical University Shuang Ho HospitalRecruiting

New Taipei City, 235, Taiwan

Taichung Veterans General HospitalRecruiting

Taichung, 407, Taiwan

National Taiwan University HospitalRecruiting

Taipei, 10002, Taiwan

Taipei Veterans General HospitalRecruiting

Taipei, 11217, Taiwan

Adana Medical Park Seyhan HastanesiRecruiting

Adana, 01140, Turkey (Türkiye)

Adana City HospitalRecruiting

Adana, 01370, Turkey (Türkiye)

Hacettepe Universite HastaneleriRecruiting

Ankara, 06230, Turkey (Türkiye)

Local Institution - 0362Not yet recruiting

Ankara, 06800, Turkey (Türkiye)

Medipol Mega Universite HastanesiRecruiting

Istanbul, 34214, Turkey (Türkiye)

TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir HastanesiRecruiting

Istanbul, 34722, Turkey (Türkiye)

Local Institution - 0441Withdrawn

Exeter, Devon EX2 5DW, United Kingdom

Local Institution - 0349Completed

Dundee, Dundee City DD1 9SY, United Kingdom

Local Institution - 0271Completed

Larbert, Falkirk FK5 4WR, United Kingdom

Local Institution - 0189Not yet recruiting

Glasgow, Glasgow City g12OYN, United Kingdom

Local Institution - 0021Withdrawn

London, Kensington and Chelsea SW3 6JJ, United Kingdom

Leicester Royal InfirmaryRecruiting

Leicester, Leicestershire LE1 5WW, United Kingdom

St Bartholomew's HospitalRecruiting

London, London, City of EC1A 7BE, United Kingdom

Local Institution - 0001Not yet recruiting

London, London, City of SE1 9RT, United Kingdom

Sarah Cannon Research Institute UKRecruiting

London, W1G 6AD, United Kingdom

Local Institution - 0020Withdrawn

Manchester, M20 4BX, United Kingdom

Local Institution - 0024Withdrawn

Metropolitan Borough of Wirral, CH63 4JY, United Kingdom

Royal Berkshire HospitalRecruiting

Reading, RG1 5AN, United Kingdom