Dinoprostone Versus Vaginal Misoprostol for Induction of Labour

Vaginal Dinoprostone Versus Vaginal Misoprostol for Induction of Labour in Post-dated Pregnancy; a Randomized Controlled Study.

This randomized controlled study was carried out on 370 pregnant women with gestational age ≥ 40 weeks of different ages and parities at El-Shatby Maternity University Hospital after approval of ethical committee of Alexandria Faculty of Medicine. After assessment for eligibility & enrollment in the study, women were randomly assigned into one of the two study groups, Group (I) received 3 mg vaginal Dinoprostone of maximum 2 doses 6 hours apart and Group (II) received 50 μg of vaginal misoprostol of maximum 2 doses 6 hours apart.

Inclusion Criteria:

• pregnant women at 40 weeks or beyond
• singleton pregnancy
• Bishop score 4 or more
• fetus in a cephalic presentation
• Adequate fetal biophysical profile

Exclusion Criteria:

• Any signs of labour (Prelabor rupture of membranes)
• Grand Multiparous women (parity of 4 or more)
• IUFD
• fetal weight > 4 kg
• BMI > 35