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| Name | Class |
|---|---|
| The German Heart Foundation | OTHER |
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The goal of this prospective observational study is to learn about the influence of epicardial fat on the success of catheter ablation in patients with atrial fibrillation.
A volumetric quantification of epicardial fat is examined by dual source cardiac computet tomography in patients with paroxysmal or persistent atrial fibrillation prior to receiving their first catheter ablation for atrial fibrillation. After ablation the recurrence of arrhythmia is examined after 3 and 6 months respectively.
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| Measure | Description | Time Frame |
|---|---|---|
| Influence of epicardial adipose tissue (EAT) volume on 1 year arrhythmia recurrences after catheter ablation | influence of EAT volume quantified by volumetric CT segmentation on 1 year arrhythmia recurrences after catheter ablation for paraxysmal or persistent atrial fibrillation | measurement of epicardial fat at baseline; anamnestic and ECG-control of arrhythmia after 3, 6 and 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| associations between EAT and gender, BMI, cholesterol levels, body fat | associations between EAT and gender, BMI, cholesterol levels, body fat | measurement of epicardial fat at baseline; anamnestic and ECG-control of arrhythmia after 3, 6 and 12 months |
| associations between EAT and left atrial wall thining |
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Inclusion Criteria:
Exclusion Criteria:
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at least 200 patients planned
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| Name | Affiliation | Role |
|---|---|---|
| Nico Erhard, Dr. med. | Deutsches Herzzentrum München | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Deutsches Herzzentrum | München | 80634 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41541734 | Derived | Englert F, Obermeyer T, Bahlke F, Popa M, Krafft H, Martinez AT, Syvari J, Tydecks M, Dischel D, Koops E, Reiter T, Telishevska M, Lengauer S, Bressem K, Hadamitzky M, Hessling G, Deisenhofer I, Erhard N. Epicardial adipose tissue and ablation outcomes in obese patients with paroxysmal atrial fibrillation: A comparison of pulsed field and radiofrequency ablation. Heart Rhythm O2. 2025 Sep 25;6(12):1901-1910. doi: 10.1016/j.hroo.2025.09.020. eCollection 2025 Dec. |
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associations between EAT and left atrial wall thining |
| measurement of epicardial fat at baseline; anamnestic and ECG-control of arrhythmia after 3, 6 and 12 months |
| associations between EAT and low voltage areas quantified by high density electroanatomical mapping | associations between EAT and low voltage areas quantified by high density electroanatomical mapping | measurement of epicardial fat and catheter ablation at baseline |
| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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