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This study aims to explore the clinical effect of THRIVE in improving early postoperative atelectasis in patients undergoing long-term non-intubated anesthesia gastrointestinal endoscopy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Transnasal humidified rapid insufflation ventilatory exchange(THRIVE) group | Experimental |
| |
| conventional oxygen mask group | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transnasal humidified rapid insufflation ventilatory exchange(THRIVE) | Procedure | Transnasal humidified rapid insufflation ventilatory exchange(THRIVE) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of atelectasis | Lung ultrasound examination was performed before anesthesia induction (T1) and immediately after surgery (T2), and patients' modified lung ultrasound score (LUSS) was recorded. | Early postoperative period |
| Measure | Description | Time Frame |
|---|---|---|
| Diaphragm movement | Before anesthesia induction (T1) and immediately after surgery (T2) | |
| Heart rate (HR) | Throughout the procedure, the heart rate (HR) was continuously monitored. | Baseline,during surgery and arrived at PACU |
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Inclusion Criteria:
5.Informed consent, voluntary participation in the experiment, and signed by the subject informed consent
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northern Jiangsu People's Hospital | Yangzhou | Jiangsu | 225000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42265606 | Derived | Song S, Meng M, Han Y, Wang X, Liu X, Gao J. Effect of transnasal humidified rapid insufflation ventilator exchange on early postoperative atelectasis in patients undergoing prolonged non-intubated anesthesia: a randomized clinical trial. BMC Anesthesiol. 2026 Jun 10. doi: 10.1186/s12871-026-03989-4. Online ahead of print. |
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| conventional oxygen mask | Procedure | conventional oxygen mask |
|
| Pulse oxygen saturation (SpO2) | Throughout the procedure, the pulse oxygen saturation (SpO2) were continuously monitored. | Baseline,during surgery and arrived at PACU |
| Mean blood pressure (MBP) | Throughout the procedure, the mean blood pressure (MBP) was measured at 3-minute intervals. | Baseline,during surgery and arrived at PACU |
| Patient satisfaction levels | The patients express their satisfaction with procedures on a numerical rating scale, ranging from 0 to 10, where 0 is the minimum and 10 is the maximum satisfaction level. | After the patient is awake |
| Endoscopist satisfaction levels | The Endoscopists express their satisfaction with procedures on a numerical rating scale, ranging from 0 to 10, where 0 is the minimum and 10 is the maximum satisfaction level. | After the surgery |
| Adverse Events (AEs) During Surgery and PACU | radycardia; Hypertension; Hypotension; Hypoxemia; Aspiration and Regurgitation | During surgery and PACU |
| Adverse Events (AEs) Within 7 Days Post-Operatively | Fever; Cough and Sputum Production; Antibiotic Usage | Within 7 days after surgery |
| PACU Stay Duration | The time from entering PACU to improving Aldrete score ≥9 |
| Length of Hospital Stay | The time from admission to discharge |
| Dosage of propofol | During surgery |
| Dosage of remifentanil | During surgery |