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Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated. The success of autotransplantation is influenced by diverse factors, including root development stage, tooth morphology, surgical technique, extraoral duration, recipient socket shape, recipient bed vascularity, and periodontal ligament cell vitality. Preserving periodontal ligament quality and achieving tissue adaptation are pivotal for successful tooth transplantation. Successful donor tooth replacement is influenced by variables like fitting attempts, alveolus-root distance, extra-alveolar time, surgical skill, and extraction trauma intensity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Autotransplantation with PRF | Experimental |
| |
| Autotrasplantation only | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Autotransplantation with PRF | Procedure | Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth with the application of PRF |
|
| Measure | Description | Time Frame |
|---|---|---|
| Radiographic success | The success of auto-transplanted immature third molars with and without Platelet-Rich Fibrin will be assessed over a year period. | one year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Luis M De la Rosa, DDS | Contact | 917-861-5881 | l.delarosa@cdiohio.org | |
| Nelza Baladi, DDS | Contact | n.baladi@cdiohio.org |
| Name | Affiliation | Role |
|---|---|---|
| Waleed Elmallah, DDS | Cleveland Dental | Study Chair |
| Ahmed Hashem, DDS | Cleveland Dental | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cleveland Dental Institute | Recruiting | Cleveland | Ohio | 44128 | United States |
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| ID | Term |
|---|---|
| D014182 | Transplantation, Autologous |
| D056690 | Prolactin-Releasing Hormone |
| ID | Term |
|---|---|
| D014180 | Transplantation |
| D013514 | Surgical Procedures, Operative |
| D007028 | Hypothalamic Hormones |
| D036361 | Peptide Hormones |
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| Autotransplatation Only | Procedure | Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth. |
|
| D006728 |
| Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D009479 | Neuropeptides |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D009419 | Nerve Tissue Proteins |
| D011506 | Proteins |