The study is a prospective observational study designed to determine the effects of central sensitization on pain and functional status of patients before and after total knee joint replacement surgery.

The aim of this study is to evaluate whether there is a difference in preoperative and postoperative pain and functional status between patients with and without central sensitization with knee osteoarthritis.

When the literature was reviewed, it was seen that central sensitization was one of the important mechanisms that caused pain in knee osteoarthritis, and it was determined that this had negative consequences in terms of postoperative pain and improvement in functional status. In this study, the effect of central sensitization on the results will be investigated by evaluating pain and functional status before and after knee total joint prosthesis in two groups of knee osteoarthritis patients, with and without central sensitization, and by comparing the groups.

Inclusion Criteria:

• Diagnosis of primary knee osteoarthritis
• Planning for total joint replacement surgery for the knee
• Being between the ages of 60-75

Exclusion Criteria:

• Having secondary knee osteoarthritis
• Planning for knee total joint prosthesis revision
• Having uncontrolled systemic disease (such as diabetes mellitus, hypertension, thyroid disease)
• Having neuromuscular disease
• Having a body mass index over 40

The study population consists of patients who were planned to have total knee arthroplasty for primary knee osteoarthritis