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This study aims to:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Observational Group | Inclusion Criteria
a) Left atrial thrombus or left atrial appendage thrombus; b) Severe chronic obstructive pulmonary disease (FEV1/ FVC<70%, FEV1<50% predicted value); c) Absolute contraindications of anticoagulation therapy; d) Currently pregnant; e) Contraindications for LGE-MRI (claustrophobia, pacemaker implantation, eGFR<30ml/min for renal insufficiency, severe obesity, pregnancy, gadolinium chelating agent allergy, etc.); f) refuse to participate in the study; g) other physical or mental incapacity to participate in the study. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| LGE-MRI Scan | Diagnostic Test | Participants will receive LGE-MRI scan before catheter ablation and 3 months after catheter ablation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Consistency of LGE-MRI fibrosis and EAM low-voltage area | Use Registration to match the corresponding spatial points of LGE-MRI and EAM。Each spatial points will contain two types of status(Fibrosis: Yes/No, Low-voltage area: Yes/No). Chi-square test will be used to assess the consistency of fibrosis and low-voltage area. | Baseline (at recruit time point) |
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Inclusion Criteria:
Exclusion Criteria:
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Adult AF patients who are planned to receive catheter ablation and have no contraindications of LGE-MRI
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai Hospital, CAMS&PUMC | Recruiting | Beijing | Beijing Municipality | 100037 | China |
IPD will be shared under the permission of primary investigator
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |