The purpose of establishing the biobank is to create a collection of biological material and clinical data, with a prospective and retrospective mold, in order to investigate the role of genetic predisposition in multifactorial bilio-pancreatic diseases, so that an evaluation of the possible association in the pathogenesis of exogenous factors with endogenous factors can be allowed.

Multifactorial diseases are in fact an expression of genetic predisposition upon which one or more environmental stimuli act. Usually the aforementioned factors are not capable individually of triggering disease but, when simultaneously present, can cause the pathological phenotype. Therefore, it becomes important in the description of disease pathogenesis to identify as many risk factors for disease prevention and early diagnosis.

Samples collected depending on the disease:

• Peripheral blood;
• Portal blood;
• Saliva;
• Urine;
• Stool;
• Cystic fluid;
• Pancreatic juice;
• Biopsy tissue specimens;

Inclusion Criteria:

• age >= 18 years
• signed informed consent

Exclusion Criteria:

• age < 18 years
• unwilling to sign informed consent

Patients with biliopancreatic disorders