Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery

Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery: a Randomized Controlled Prospective Study

The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are:

1. does Transversus Thoracic Plane Block decrease perioperative pain after cardiac surgery more than the standard analgesic treatment?
2. Are the results different if the investigators perform Transversus Thoracic Plane Block before surgery or at the end of surgery?

Inclusion Criteria:

- All patients scheduled for cardiac surgery via sternotomy under cardiopulmonary bypass

Exclusion Criteria:

• Previous cardiac surgery
• Urgent surgery
• Pregnant women
• Allergy to local anesthetics
• Opioid dependence
• Low ejection fraction < 30%
• Presence or onset of cognitive or neurological disorders preventing pain assessment
• Infection at injection sites
• Coagulopathy
• Patients on dual antiplatelet therapy
• Renal insufficiency with Glomerular filtration rate (GFR) < 30 mL/min
• History of thoracic radiotherapy
• History of mastectomy