American Indian Smokefree Native RCT

Randomized Clinical Trial of A Culturally Aligned Digital Smoking Cessation Resource for American Indian Persons

The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.

This is a two-arm, parallel group, randomized controlled clinical trial. Eligible participants (n=416) will be randomized to either the culturally aligned resource or the general audience version. Participants will use the assigned resource for 6 months, and partake in surveys at baseline, and 1, 3 and 6 months, during which they will be asked several questions related to use of their assigned resource, and smoking behavior. Carbon monoxide (CO) in exhaled breath will be collected at 1, 3 and 6 months using iCO™ Smokerlyzer® (https://www.icoquit.com/us/).

Inclusion Criteria:

• AI race based on self-report;
• ≥ 18 years of age via photo ID confirmation;
• Average smoked cigarettes per day, ≥ 3 in the past 30 days;
• considering or willing to make a quit attempt;
• self-report having daily access to their own iPhone/Android smartphone or tablet that allows for messaging use;
• able to read and speak English.

Exclusion Criteria:

• None