Effect of Prophylactic Application of 40Hz Transcranial Stimulation in AICU on Incidence of Postoperative Delirium in Elderly Patients Undergoing Elective Gastrointestinal Surgery

Effect of Prophylactic Application of 40Hz Transcranial Stimulation in AICU on Incidence of Postoperative Delirium in Elderly Patients Undergoing Elective Gastrointestinal Surgery

Postoperative delirium is an acute central nervous system dysfunction caused by surgical stress, which is manifested by postoperative acute, non-specific changes in consciousness level, attention, cognitive ability and disturbance of sleep and wake cycles. It is one of the most common surgical complications in the elderly, occurring in more than 75% of patients receiving mechanical ventilation in the intensive care unit(ICU).Exogenous 40 Hz stimulation can improve cognitive functioning.Therefore, the aim of this study was to investigate the effect of exogenous 40Hz stimulation on the incidence of postoperative delirium in elderly patients undergoing elective gastrointestinal surgery in AICU.

Inclusion Criteria:

• 1.Age ≥ 65 years old,gender not limited
• 2.ASA classification Ⅱ ~ Ⅳ
• 3.Elective gastrointestinal general anesthesia surgery

Exclusion Criteria:

• 1.History of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis
• 2.Pre-operative coma, severe dementia, speech impairment or severe illness incapacitated and unable to communicate
• 3.Delirium on admission or pre-operative delirium, brain injury
• 4.Severely infected person
• 5.Severe liver dysfunction (Child-Pugh C), severe renal insufficiency (preoperative dialysis)
• 6.Severe hearing or vision impairment