Steps Against the Burden of Parkinson's Disease - StepuP

Steps Against the Burden of Parkinson's Disease - StepuP

The goals of our StepuP project are:

1. To understand the kinematic and neural mechanisms underlying walking improvements due to treadmill training with and without VR-enabled gait adaptations in people with PD;
2. To assess to what extent improvements in walking due to treadmill training, as measured in the laboratory, transfer to improvements in daily life mobility;
3. To understand the mechanisms underlying the transfer from improvements in walking to improvements in mobility in daily life in people with PD;
4. To understand for whom treadmill training improves walking characteristics in the laboratory and for whom it does not, and to understand for whom treadmill training improves mobility in daily life and for whom it does not.

Inclusion Criteria:

Specific criteria for Parkinson's disease - PD

• Diagnosis of Parkinson's disease according to the MDS World Movement Disorders Society criteria Disease severity H&Y I-III
• Score section 3.10 (ability to walk) MDS-UPDRS 3.10 ≥ 1
• MoCA cognitive assessment > 15
• Stable cardiovascular condition, ability to perform aerobic activity at low to moderate intensity
• Without orthopedic diseases and other diseases that affect the quality of walking, at the decision of the researcher.

Exclusion Criteria:

• Moderate or severe depression (BDI-II ≥18)
• Orthopedic diseases and other diseases that affect the quality of walking, at the decision of the researcher